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Copper modifies liver microsomal UDP-glucuronyltransferase activity through different and opposite mechanisms
(ELSEVIER IRELAND LTD, 2007-04)
Treatment of hepatic microsomes with Fe3+/ascorbate activates UDP-glucuronyltransferase (UGT), a phenomenon totally prevented
and reversed by reducing agents. At #2;M concentrations, iron and copper ions catalyze the ...
Poliformismo no genes ugt1a1 e bcl11a: rela????o com fatores laboratoriais e com a resposta a hidroxiureia em pacientes com anemia falciforme
(Escola de MedicinaPrograma de P??s Gradua????o em PatologiaUFBAbrasil, 2017-10-04)
Association of UGT2B7, UGT1A9, ABCG2, and IL23R polymorphisms with rejection risk in kidney transplant patients
(2017-08-03)
Despite advances in testing compatibility between donor and recipient, graft rejection remains a current concern. Single-nucleotide polymorphisms (SNPs) that codify altered enzymes of metabolism, drug transport, and the ...
Glucuronidation of apomorphine
(Elsevier, 2000-08-25)
Apomorphine, a dopaminergic receptor agonist, is largely used in the therapy of Parkinson's disease. In this study, we characterized the glucuronidation of apomorphine and other catechols in rat liver and brain microsomes, ...