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Expression of multiple Sox genes through embryonic development in the ctenophore Mnemiopsis leidyi is spatially restricted to zones of cell proliferation
(2014-04-24)
Abstract
Background
The Sox genes, a family of transcription factors characterized by the presence of a high mobility group (HMG) box domain, are among the central groups of developmental regulators ...
Comparative cytogenetic mapping of Sox2 and Sox14 in cichlid fishes and inferences on the genomic organization of both genes in vertebrates
(Springer, 2011-07-01)
To better understand the genomic organization and evolution of Sox genes in vertebrates, we cytogenetically mapped Sox2 and Sox14 genes in cichlid fishes and performed comparative analyses of their orthologs in several ...
Dimerization and Transactivation Domains as Candidates for Functional Modulation and Diversity of Sox9
(2016-05-01)
Sox9 plays an important role in a large variety of developmental pathways in vertebrates. It is composed of three domains: high-mobility group box (HMG box), dimerization (DIM) and transactivation (TAD). One of the main ...
Genome-wide association studies identify DNA variants influencing eyebrow thickness variation in Europeans and across continental populations.
(Elsevier, 2023)
Ethics. Human subjects: All cohort participants gave written informed consent and consent to publish. Ethical approvals were provided for the Rotterdam Study according to the Population Study Act Rotterdam Study (Wet ...
The clinical impact of chromosomal rearrangements with breakpoints upstream of the SOX9 gene: two novel de novo balanced translocations associated with acampomelic campomelic dysplasia
(2013)
Abstract
Background
The association of balanced rearrangements with breakpoints near SOX9 [SRY (sex determining region Y)-box ...
The clinical impact of chromosomal rearrangements with breakpoints upstream of the SOX9 gene: two novel de novo balanced translocations associated with acampomelic campomelic dysplasia
(2013-05-07)
Abstract
Background
The association of balanced rearrangements with breakpoints near SOX9 [SRY (sex determining region Y)-box 9] with skeletal abnormalities ...
The clinical impact of chromosomal rearrangements with breakpoints upstream of the SOX9 gene: two novel de novo balanced translocations associated with acampomelic campomelic dysplasia
(2013-05-07)
Abstract
Background
The association of balanced rearrangements with breakpoints near SOX9 [SRY (sex determining region Y)-box 9] with skeletal abnormalities ...
Spinal cord regeneration in Xenopus tadpoles proceeds through activation of Sox2-positive cells
(2012)
Abstract
Background
In contrast to mammals, amphibians, such as adult urodeles (for example, newts) and anuran larvae (for example, Xenopus) can regenerate their spinal ...
Regulação da região promotora de genes do sistema renina-angiotensina pelas proteínas SRY e SOX3
(Universidade Federal de Minas GeraisUFMG, 2015-04-01)
The renin-angiotensin system (RAS) is subject to sex-specific modulation by hormones and gene products. However, sex-differences in the balance between the vasoconstrictor/proliferative ACE (angiotensin-converting enzyme)/Ang ...