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The role of regulatory T Cells in autoimmune orchitis
(Wiley Blackwell Publishing, Inc, 2018-12)
Regulatory T cells (Tregs) mediate tolerance to self-antigens maintaining immune homeostasis. Defects in the number and function of Tregs lead to aberrant immune responses to autologous components, thereby causing autoimmune ...
CD4+Foxp3+T regulatory cells promote transplantation tolerance by modulating effector CD4+ T cells in a neuropilin-1-dependent manner
(Frontiers Media S.A., 2019)
Copyright © 2019 Campos-Mora, Contreras-Kallens, Gálvez-Jirón, Rojas, Rojas, Refisch, Cerda and Pino-Lagos.Several mechanisms of immune suppression have been attributed to Foxp3+ T regulatory cells (Treg) including modulation ...
Limited Foxp3+ regulatory T cells response during acute Trypanosoma cruzi infection is required to allow the emergence of robust parasite-specific CD8+ T cell immunity
(Frontiers Media S.A., 2018-11)
While it is now acknowledged that CD4+ T cells expressing CD25 and Foxp3 (Treg cells) regulate immune responses and, consequently, influence the pathogenesis of infectious diseases, the regulatory response mediated by Treg ...
Imbalanced expression of functional surface molecules in regulatory and effector T cells in systemic lupus erythematosus
(Associação Brasileira de Divulgação Científica, 2014-08-01)
Regulatory T (TREG) cells play an important role in maintaining immune tolerance and avoiding autoimmunity. We analyzed the expression of membrane molecules in TREG and effector T cells in systemic lupus erythematosus ...
Differences in T regulatory cells between mouse strains frequently used in immunological research: Treg cell quantities and subpopulations in NOD, B6 and BALB/c mice
(Elsevier Science, 2020-07)
Foxp3+ Regulatory T cells (Tregs) are essential for the maintenance of tolerance to self. Therefore, it is expected that lower numbers and/or less than optimal function could impact on the functioning of the immune system, ...
Regulatory T lymphocytes in periodontitis: A translational view
(Hindawi Ltd, 2018)
Periodontitis is a chronic immuno-inflammatory disease in which the disruption of the balance between host and microbiota interactions is key to the onset and progression of the disease. The immune homeostasis associated ...
Th17 and Treg cells, two new lymphocyte subpopulations with a key role in the immune response against infection
(2008)
In addition to the T helper 1 (Th1) and Th2 lymphocyte subsets, two new subpopulations Th17 and regulatory T
(Treg) cells have recently been described. Th17 cells, which produce high levels of interleukin (IL)-17, ...
Expansion of CD25-Negative Forkhead Box P3-Positive T Cells during HIV and Mycobacterium tuberculosis Infection
(Frontiers Research Foundation, 2017-05)
Tuberculosis (TB) and HIV alter the immune system, and coinfected (HIV-TB) individuals usually present deregulations of T-lymphocytic immune response. We previously observed an increased frequency of “unconventional” ...