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Neurotoxins as Preclinical Models for Parkinson’s Disease
(Springer New York LLC, 2018)
© 2018, Springer Science+Business Media, LLC, part of Springer Nature.Translational medicine is one of the major concerns in this century. While significant advances have been made with scientific knowledge, the translation ...
Humanized mouse models of rheumatoid arthritis for studies on immunopathogenesis and preclinical testing of cell-based therapies
(Frontiers Media S.A., 2019)
Copyright © 2019 Schinnerling, Rosas, Soto, Thomas and Aguillón. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other ...
The importance of choosing a preclinical model that reflects what happens in Parkinson's disease
(Elsevier Ltd, 2019)
One of the major problems in the translation of successful preclinical results to clinical studies and new therapies in Parkinson's disease is the use of preclinical models based on exogenous neurotoxins that do not replicate ...
Humanized Mouse Models of Rheumatoid Arthritis for Studies on Immunopathogenesis and Preclinical Testing of Cell-Based Therapies
(Facultad de Medicina y Ciencia, 2019)
Rodent models of rheumatoid arthritis (RA) have been used over decades to study the immunopathogenesis of the disease and to explore intervention strategies. Nevertheless, mouse models of RA reach their limit when it comes ...
Commentary: Evaluation of models of Parkinson's disease
(Frontiers Media S.A., 2016)
Commentary: A humanized clinically calibrated quantitative systems pharmacology model for hypokinetic motor symptoms in Parkinson's disease
(Frontiers Research Foundation, 2016)
Commentary: Evaluation of Models of Parkinson's Disease
(Frontiers Media, 2016-04)
Aminochrome as preclinical model for Parkinson's disease
(Impact Journals LLC, 2017)