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Influence of bisphosphonates on the behavior of osteoblasts seeded onto titanium discs
(2020-05-01)
Among other factors, types of bisphosphonates and treatment regimens seem to be strongly associated with the success or failure of installation of osseointegrated implants. This study investigated the influence of two ...
Fibroblast and pre-osteoblast cell adhesive behavior on titanium alloy coated with diamond film
(2017-01-01)
It is well known that titanium alloys have mechanical strengths comparable to steels, as well as high corrosion resistance. Also, they have the advantage of promoting osseointegration, when used in medical and dental ...
Nano hydroxyapatite-blasted titanium surface affects pre-osteoblast morphology by modulating critical intracellular pathways
(2017-08-01)
Although, intracellular signaling pathways are proposed to predict the quality of cell-surface relationship, this study addressed pre-osteoblast behavior in response to nano hydroxyapatite (HA)-blasted titanium (Ti) surface ...
TNF alpha contributes for attenuating both Y(397)FAK and Y(416)Src phosphorylations in osteoblasts
(Wiley-Blackwell, 2014-11-01)
ObjectiveOur poor understanding of how inflammatory mediators can affect osteoblast behavior led us to investigate the tumor necrosis factor (TNF)-induced focal adhesion kinase (FAK) and Src phosphorylation.Material and ...
First insight on the impact of an osteoblastic layer on the bio-tribocorrosion performance of Ti6Al4V hip implants
(Elsevier B.V., 2015-01-15)
In uncemented Ti6Al4V hip implants, the bone-stem interface is subjected to cyclic loading motion driven by the daily activities of the patients, which may lead to the complete failure of the implant in the long term. It ...
Modulatory effects of silibinin in cell behavior during osteogenic phenotype
(2019-08-01)
Natural molecules, such as flavonoid, are very welcome strategies to modulate bone turnover. This prompted us to comprehend better the effect of silibinin on osteoblast metabolism, mainly considering intracellular pathways ...
Osteoblast response to porous titanium and biomimetic surface: In vitro analysis
(Elsevier B. V., 2015)
This study analyzed the behavior of human osteoblasts cultured on porous titanium specimens, with and without biomimetic treatment, compared to dense titanium. The experiment had seven groups: Group 1: cells cultured on ...