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The ‘thanato-resistome’ - The funeral industry as a potential reservoir of antibiotic resistance: Early insights and perspectives
The funeral industry is
a potential reservoir of antibiotic resistance. The occurrence,
human exposure and health risks of antibiotic resistance in the funeral industry were examined. The funeral industry harbours ...
Hybrid inhalable microparticles for dual controlled release of levofloxacin and DNase: Physicochemical characterization and in vivo targeted delivery to the lungs
(Royal Society of Chemistry, 2016-03)
Current medical treatments against recurrent pulmonary infections caused by Pseudomonas aeruginosa, such as cystic fibrosis (CF) disorder, involve the administration of inhalable antibiotics. The main challenge is, however, ...
Fast Biofilm Penetration and Anti-PAO1 Activity of Nebulized Azithromycin in Nanoarchaeosomes
(American Chemical Society, 2020-01)
Azithromycin (AZ) is a broad-spectrum antibiotic with anti-inflammatory and antiquorum sensing activity against biofilm forming bacteria such as Pseudomonas aeruginosa. AZ administered by oral or parenteral routes, however, ...
Incorporation of antibiotics in liposomes designed for tuberculosis therapy by inhalation
(Taylor & Francis IncPhiladelphiaEUA, 2003)
Avaliação da resposta clínica ao uso de antibióticos por via oral e via inalatória em pacientes portadores de bronquiectasias
(Associação Médica Brasileira, 1999-07-01)
INTRODUCTION. The aim of this technique was to achieve high concentration of the antibiotic that excedeed the minimal inhibitory concentration (MIC) of the microbial load present in the sputum. METHOD. To evaluate the ...
Optimization of Ciprofloxacin Hydrochloride Spray-Dried Microparticles for Pulmonary Delivery Using Design of Experiments
(Springer, 2018-10)
Ciprofloxacin is a broad-spectrum antibiotic for treatment of pulmonary diseases such as chronic obstructive pulmonary disease and cystic fibrosis. The purpose of this work was to rationally study the spray drying of ...