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Desenvolvimento de nanocápsulas poliméricas contendo Indol-3-Carbinol e avaliação biológica das formulações
(Universidade Federal de Santa MariaBrasilFarmacologiaUFSMPrograma de Pós-Graduação em Ciências FarmacêuticasCentro de Ciências da Saúde, 2016-08-08)
Indole-3carbinol (I3C) is a phytochemical that has several therapeutic properties. However, it is unstable
against acid and light conditions. In this sense, polymeric nanocapsules are interesting alternatives for
the ...
Indole-3-carbinol attenuates the deleterious gestational effects of bisphenol A exposure on the prostate gland of male F1 rats
(Elsevier B.V., 2014-01-01)
Bisphenol A (BPA) is a chemical that has been investigated for it potential to cause prostate diseases. In this study, pregnant Sprague-Dawley rats were treated with 25 or 250 mu g/kg BPA from gestational day (GD) 10 to ...
Are the phytochemicals genistein and indole-3-carbinol able to reverse the hormonal imprinting caused by bisphenol A in the prostate of rats?
(Amer Soc Cell Biology, 2015-01-01)
Enhancement of colon carcinogenesis by the combination of indole-3 carbinol and synbiotics in hemin-fed rats
(2018-02-01)
The risk of developing colorectal cancer (CRC) could be associated with red and processed meat intake. Experimental data supports that hemin iron, found abundantly in red meat, promotes CRC in mice and rats, while indole-3 ...
Global gene expression and morphological alterations in the mammary gland after gestational exposure to bisphenol A, genistein and indole-3-carbinol in female Sprague-Dawley offspring
(2016-07-15)
This study aimed to evaluate the modifying effects of dietary genistein (GEN) and indole-3-carbinol (I3C) on early mammary gland development in female Sprague-Dawley offspring born to mothers exposed to BPA during gestation. ...
Efecto de derivados de Indol-3-Carbinol sobre viabilidad, muerte y migración celular en líneas celulares de cáncer
(Universidad de Valparaíso, 2015)
El cáncer es una enfermedad causada por cambios en los genes que controlan la forma
en cómo funcionan nuestras células, especialmente la forma en que crecen y se dividen. Las células cancerosas pueden ignorar las señales ...