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Epigenetic control and cancer: the potential of histone demethylases as therapeutic targets
(Pharmaceuticals, 2012-06-26)
The development of cancer involves an immense number of factors at the molecular level. These factors are associated principally with alterations in the epigenetic mechanisms that regulate gene expression profiles. Studying ...
Evolution of the histones: free play with exon shuffling
(Sociedad de Biología de Chile, 2001)
Comparative effects of histone deacetylases inhibitors and resveratrol on Trypanosoma cruzi replication, differentiation, infectivity and gene expression
(Elsevier, 2017-04)
Histone post-translational modification, mediated by histone acetyltransferases and deacetylases, is one of the most studied factors affecting gene expression. Recent data showing differential histone acetylation states ...
Histone Deacetylase 1 Is Essential for Rod Photoreceptor Differentiation by Regulating Acetylation at Histone H3 Lysine 9 and Histone H4 Lysine 12 in the Mouse Retina
(Amer Soc Biochemistry Molecular Biology Inc, 2017)
Histone acetylation has a regulatory role in gene expression and is necessary for proper tissue development. To investigate the specific roles of histone deacetylases (HDACs) in rod differentiation in neonatal mouse retinas, ...
Supplementation with the histone deacetylase inhibitor trichostatin A during in vitro culture of bovine embryos
(2013-02-01)
Summary Trichostatin A (TSA) is a histone deacetylase inhibitor that induces histone hyperacetylation and increases gene expression levels. The aim of the present study was to establish a suitable condition for the use of ...
Supplementation with the histone deacetylase inhibitor trichostatin A during in vitro culture of bovine embryos
(2013-02-01)
Summary Trichostatin A (TSA) is a histone deacetylase inhibitor that induces histone hyperacetylation and increases gene expression levels. The aim of the present study was to establish a suitable condition for the use of ...
Schistosoma mansoni histone acetyltransferase GCN5: linking histone acetylation to gene activation
(Elsevier B.V., 2004-01-01)
Chromosome Mapping of H1 Histone and 5S rRNA Gene Clusters in Three Species of Astyanax (Teleostei, Characiformes)
(Karger, 2011-01-01)
We report here on the physical mapping of the H1 histone genes (hisDNA) and the 5S ribosomal DNA (rDNA) in 3 Neotropical fish species of the genus Astyanax (A. altiparanae, A. bockmanni and A. fasciatus) and the comparative ...
Chromosome Mapping of H1 Histone and 5S rRNA Gene Clusters in Three Species of Astyanax (Teleostei, Characiformes)
(Karger, 2011-01-01)
We report here on the physical mapping of the H1 histone genes (hisDNA) and the 5S ribosomal DNA (rDNA) in 3 Neotropical fish species of the genus Astyanax (A. altiparanae, A. bockmanni and A. fasciatus) and the comparative ...