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Patients with advanced oral squamous cell carcinoma have high levels of soluble E-cadherin in the saliva
(Medicina Oral, 2017)
Background: The objective of this study was to assess the potential clinical value of the concentration of soluble salivary E-cadherin (sE-cadherin) compared with the clinical value of the resence of membranous E-cadherin ...
P120-Catenin Regulates Early Trafficking Stages of the N-Cadherin Precursor Complex
(Public Library of Science, 2016-06)
It is well established that binding of p120 catenin to the cytoplasmic domain of surface cadherin prevents cadherin endocytosis and degradation, contributing to cell-cell adhesion. In the present work we show that p120 ...
E-cadherin and beta-catenin Loss of Expression Related to Bone Metastasis in Prostate Cancer
(LIPPINCOTT WILLIAMS & WILKINS, 2010)
Objectives: E-cadherin and beta-catenin are adhesion molecules responsible for the maintenance of normal epithelial cell phenotype. A disturbance in epithelial cell adhesion, which leads to a more invasive and metastatic ...
Immune expression of E-cadherin and alpha, beta and gamma-Catenin adhesion molecules and prognosis for upper urinary tract urothelial carcinomas
(BRAZILIAN SOC UROLRIO DE JANEIRO, 2012)
Introduction: Cell adhesion molecules (CAM) are required for maintaining a normal epithelial phenotype, and abnormalities in CAM expression have been related to cancer progression, including bladder urothelial carcinomas. ...
Expression of epithelial cadherin in the human male reproductive tract and gametes and evidence of its participation in fertilization
(Oxford University Press, 2008-12)
Epithelial cadherin (E-cadherin) has been involved in several calcium-dependent cell-cell adhesion events; however, its participation in gamete interaction has not been fully investigated. Our results have demonstrated ...
E-cadherin in canine mast cell tumors: Decreased expression and altered subcellular localization in Grade 3 tumors
(ELSEVIER SCI LTDOXFORD, 2012)
Mast cell tumors (MCTs) are the most frequent round cell tumors in dogs and comprise approximately 21% of all canine cutaneous tumors. MCTs are highly invasive and metastatic corresponding to the histological grade. ...
E-Cadherin Downregulation is Mediated by Promoter Methylation in Canine Prostate Cancer
(2019-11-29)
E-cadherin is a transmembrane glycoprotein responsible for cell-to-cell adhesion, and its loss has been associated with metastasis development. Although E-cadherin downregulation was previously reported in canine prostate ...
Role of adhesion molecules and proliferation hyperplasic, pre neoplastic and neoplastic lesions in canine prostate
(2013-05-01)
E-cadherin and beta-catenin are component of adherens junctions in epithelial cells. Loss of these proteins have been associated with progression of prostatic diseases. We performed immunohistochemistry for E-cadherin, ...
Secretory leukocyte protease inhibitor (slpi) expression downregulates E-cadherin, induces β-catenin re-localization and triggers apoptosis-related events in breast cancer cells
(Wiley, 2014-09)
BACKGROUND INFORMATION: Epithelial cadherin (E-cadherin) is involved in cell–cell adhesion through its extracellular domain, whereas the intracellular domain interacts with adaptor proteins, i.e. β-catenin, links E-cadherin ...