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Myeloperoxidase-induced genomic DNA-centered radicals
(American Society For Biochemistry And Molecular Biology, 2010-06)
Myeloperoxidase (MPO) released by activated neutrophils can initiate and promote carcinogenesis. MPO produces hypochlorous acid (HOCl) that oxidizes the genomic DNA in inflammatory cells as well as in surrounding epithelial ...
CHEMICAL AND PHOTOCHEMICAL GENERATED CARBON-CENTERED RADICAL INTERMEDIATE AND ITS REACTION WITH DEOXYRIBONUCLEIC-ACID
(Pergamon-elsevier Science LtdOxfordInglaterra, 1995)
Trapping of DNA radicals with the nitrone spin trap 5,5-dimethyl-1-pyrroline N-oxide and genotoxic damage: Recent advances using the immuno-spin trapping technology
(Elsevier Science Inc, 2019-10)
Immuno-spin trapping detection of DNA radicals with the nitrone spin trap 5,5-dimethyl-1-pyrrloine N-oxide (DMPO) has made important contributions towards the understanding of DNA radicalization and genotoxicity at sites ...
Bixin and lycopene modulation of free radical generation induced by cisplatin-DNA interaction
(ELSEVIER SCI LTD, 2009)
This work evaluated the Modulation of reactive oxygen species (ROS) produced by the cisplatin-human DNA interaction in a cell-free experimental model by the carotenoids bixin and lycopene extracted from, natural dietary ...
Investigations of the antioxidant properties of plant extracts using a DNA-electrochemical biosensor
(Elsevier Advanced TechnologyOxfordInglaterra, 2006)
DNA damage by sulfite autoxidation catalyzed by cobalt complexes
(ROYAL SOC CHEMISTRY, 2008)
DNA damage was investigated in the presence of sulfite, dissolved oxygen and cobalt(II) complexes with glycylglycylhistidine, glycylhistidyllysine, glycylglycyltyrosylarginine and tetraglycine. These studies indicated that ...
Effect of some antioxidants on oxidative DNA damage induced by autoxidation of microquantities of sulfite in the presence of Ni(II)/Gly-Gly-L-His
(TAYLOR & FRANCIS LTD, 2010)
Ni(II)GGH (GGH, glycylglycyl-L-histidine) reacts rapidly with S(IV), in air-saturated solution, to produce Ni(III)GGH. A mechanism is proposed where Ni(III) oxidizes SO(3)(2-) to SO(3)(center dot-), which reacts with ...
Oxidative DNA damage induced by S(IV) in the presence of Cu(II) and Cu(I) complexes
(Sociedade Brasileira de Química, 2009)
The DNA damage induced by S(IV) in the presence of some Cu(II) complexes in air saturated solution was investigated. The addition of S(IV) to an air saturated solution containing CuII GGA (GGA = glycylglycyl-L-alanine), ...