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A path collective variable for extracting free energy profiles from cryo-electron microscopy
(Grupo de Magnetismo y SimulaciónMedellín - Colombia, 2022)
Macromolecule Particle Picking and Segmentation of a KLH Database by Unsupervised Cryo-EM Image Processing
(Facultad de Medicina y Ciencia, 2019)
Segmentation is one of the most important stages in the 3D reconstruction of macromolecule structures in cryo-electron microscopy. Due to the variability of macromolecules and the low signal-to-noise ratio of the structures ...
Sub-ångström cryo-EM structure of a prion protofibril reveals a polar clasp
(Nature Publishing Group, 2018-02)
The atomic structure of the infectious, protease-resistant, β-sheet-rich and fibrillar mammalian prion remains unknown. Through the cryo-EM method MicroED, we reveal the sub-ångström-resolution structure of a protofibril ...
Preparation of primary neurons for visualizing neurites in a frozen-hydrated state using cryo-electron tomography
(MyJoVE Corp., 2014-02)
Neurites, both dendrites and axons, are neuronal cellular processes that enable the conduction of electrical impulses between neurons. Defining the structure of neurites is critical to understanding how these processes ...
The effect of ionic strength on the structural organization of dioctadecyldimethylammonium bromide in aqueous solution
(Springer, 2004-01-01)
High-curvature and stabilized vesicles of dioctadecyldimethylammonium bromide (DODABr) can be formed spontaneously in aqueous electrolytic solution. It is shown by cryo-transmission electron microscopy that 5.0 mM DODABr ...
Macromolecule particle picking and segmentation of a KLH database by unsupervised Cryo-EM image processing.
Segmentation is one of the most important stages in the 3D reconstruction of macromolecule structures in cryo-electron microscopy. Due to the variability of macromolecules and the low signal-to-noise ratio of the structures ...
Macromolecule particle picking and segmentation of a KLH database by unsupervised Cryo-EM image processing.
Segmentation is one of the most important stages in the 3D reconstruction of macromolecule structures in cryo-electron microscopy. Due to the variability of macromolecules and the low signal-to-noise ratio of the structures ...
The architecture of inactivated SARS-COV-2 with postfusion spikes revealed by cryo-em and cryo-et
The ongoing global pandemic of coronavirus disease 2019 (COVID-19) resulted from the outbreak of SARSCoV-2 in December 2019. Currently, multiple efforts are being made to rapidly develop vaccines and treatments to fight ...