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Hepatotoxicity induced by coxibs: how concerned should we be?
(Informa Healthcare, 2016-11)
Introduction: The selective inhibitors of COX-2, coxibs, are nonsteroidal anti-inflammatory drugs (NSAIDs) that have much better gastrointestinal safety profile as compared with non-selective NSAIDs. In this review, we ...
Comment on: “Coxibs Refocus Attention on the Cardiovascular Risks of Non-Aspirin NSAIDs”
(Springer, 2017-12)
In a recent issue of the American Journal of Cardiovascular Drugs, Thomas et al. [1] analyzed the cardiovascular safety of cyclo-oxygenase (COX)-2 inhibitors (coxibs). In the Recommendations section of the paper, the authors ...
Nitridergic Modulation of COX-2 Efficacy
(2022)
Pain is a common unpleasant sensory and emotional experience, in which are frequently used in their treatment the nonsteroidal anti-inflammatory drugs (NSAIDs). A group of agents with antipyretic, analgesic, and anti-inflammatory ...
COX-2 Inhibitors for Cancer Treatment in Dogs
(Univ Agriculture, 2011-01-01)
Cancer is one of the main causes of death in canines and felines, and this fact is probably related to the increase in the longevity of these species. The longer the animals live, the higher the exposure to carcinogenic ...
COX-2 Inhibitors for Cancer Treatment in Dogs
(Univ Agriculture, 2011-01-01)
Cancer is one of the main causes of death in canines and felines, and this fact is probably related to the increase in the longevity of these species. The longer the animals live, the higher the exposure to carcinogenic ...
COX-2 inhibitors for cancer treatment in dogs
(2011-10-01)
Cancer is one of the main causes of death in canines and felines, and this fact is probably related to the increase in the longevity of these species. The longer the animals live, the higher the exposure to carcinogenic ...
COX-2 Inhibitors for Cancer Treatment in Dogs
(Univ Agriculture, 2014)
Effect of nonsteroidal antiinflammatory drugs NSAIDs, analgesics and coxibs on the magnitude and rate of orthodontic tooth movementEfecto de los antiinflamatorios no esteroideos AINEs, analgésicos y coxibs sobre la magnitud del movimiento dentario ortodóntico
(Universidad Nacional Mayor de San Marcos, Facultad de Odontología, 2014)
Fisiopatología y seguridad del uso de aines selectivos y no selectivos: balance de riesgos
(2011-01-04)
Los AINES son de los fármacos más utilizados hoy en día para el tratamiento del dolor agudo y crónico, por lo tanto es importante conocer el mecanismo y la magnitud de los diferentes efectos adversos de estos. En este ...