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Antiviral activity of the natural alkaloid anisomycin against dengue and Zika viruses
(Elsevier Science, 2020-04)
Flaviviruses constitute a public health concern because of their global burden and the lack of specific antiviral treatment. Here we investigated the antiviral activity of the alkaloid anisomycin against dengue (DENV) and ...
Ha-Ras sensitizes transformed mouse skin cells to Anisomycin-induced apoptosis
(ELSEVIER SCIENCE BV, 2005-11-21)
Efforts have been made to develop a chemoprevention that selectively triggers apoptosis in malignant cancer cells. Here, we demonstrated that a mutated Ha-Ras activity is required in Anisomycin-induced apoptosis in transformed ...
Evidence of two mechanisms for the activation of the glucose transporter GLUT1 by anisomycin: p38(MAP kinase) activation and protein synthesis inhibition in mammalian cells
(1997)
1. Inhibitors of protein synthesis stimulate sugar transport in mammalian cells through activation of plasma membrane GLUT1, the housekeeping isoform of the glucose transporter. However, it has been reported that some of ...
Retrieval induces reconsolidation of fear extinction memory
(National Academy of Sciences, 2010-12)
The nonreinforced expression of long-tem memory may lead to two opposite protein synthesis-dependent processes: extinction and reconsolidation. Extinction weakens consolidated memories, whereas reconsolidation allows ...
Effects of anisomycin on brain protein synthesis and passive avoidance learning in newborn chicks
(1976)
The effects of anisomycin (ANM) on newborn chicks have been studied with respect to brain protein synthesis, growth, EEG, toxicity, and several passive avoidance learning tasks. It was found that intracerebral ANM (80 nmol) ...
Actividad antiviral de alcaloides naturales y sintéticos frente a los virus dengue y ZikaAntiviral activity of natural and synthetic alkaloids against dengue and Zika viruses
(2018-03-20)
Los virus dengue (DENV) y Zika (ZIKV), pertenecientes al género Flavivirus dentro de la familia Flaviviridae, son importantes patógenos para el hombre para los cuales no se dispone aún de un tratamiento antiviral específico. ...