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Genotype analysis of the human endostatin variant p.D104N in benign and malignant adrenocortical tumors
(HOSPITAL CLINICAS, UNIV SAO PAULOSAO PAULO, 2012)
OBJECTIVE: Endostatin is a potent endogenous inhibitor of angiogenesis. It is derived from the proteolytic cleavage of collagen XVIII, which is encoded by the COL18A1 gene. A polymorphic COL18A1 allele encoding the functional ...
Histamine inhibits adrenocortical cell proliferation but does not affect steroidogenesis.
(Bioscientifica, 2014-03-07)
Histamine (HA) is a neurotransmitter synthesized in most mammalian tissues exclusively by histidine decarboxylase enzyme. Among the plethora of actions mediated by HA, the modulatory effects on steroidogenesis and proliferation ...
Effect of maternal environment on yolk immunoreactive corticosterone and its influence on adrenocortical and behavioral activity in chicks of Greater Rhea (Rhea americana)
(Academic Press Inc Elsevier Science, 2019-08)
Maternal corticosterone in avian eggs may modify offspring phenotype in order to increase survival in poor environments. In the Greater Rhea (Rhea americana), we previously found that yolk immunoreactive corticosterone is ...
The tyrosine kinase inhibitor nilotinib is more efficient than mitotane in decreasing cell viability in spheroids prepared from adrenocortical carcinoma cells
(BioMed Central, 2018)
Abstract
Background
New drugs for adrenocortical carcinoma (ACC) are needed because most patients undergo rapid disease progression despite surgery and adjuvant therapy ...
Arginine vasopressin controls p27(KiP1) protein expression by PKC activation and irreversibly inhibits the proliferation of K-Ras-dependent mouse Y1 adrenocortical malignant cells
(ELSEVIER SCIENCE BV, 2011)
The neurohypophyseal hormone arginine vasopressin (AVP) is a classic mitogen in many cells. In K-Ras-dependent mouse Y1 adrenocortical malignant cells, AVP elicits antagonistic responses such as the activation of the PKC ...
Igf2 And Igf1r In Pediatric Adrenocortical Tumors: Roles In Metastasis And Steroidogenesis
(BIOSCIENTIFICA LTDBRISTOL, 2016)
Characterization and correlations of behavioral and adrenocortical activities of zoo-housed lesser anteaters (Tamandua tetradactyla)
(Wiley, 2019-06-07)
We characterized behavioral and adrenocortical activities of Tamandua tetradactyla under human care driven by the hypothesis that they vary between males and females. We also assessed the potential association between ...
5-oxo-ETE activates migration of H295R adrenocortical cells via MAPK and PKC pathways
(Elsevier Science Inc, 2019-10)
The OXE receptor is a GPCR activated by eicosanoids produced by the action of 5-lipoxygenase. We previously found that this membrane receptor participates in the regulation of cAMP-dependent and -independent steroidogenesis ...
Assessment of adrenocortical activity and behavior of the collared anteater (Tamandua tetradactyla) in response to food-based environmental enrichment
(Wiley-liss, Div John Wiley & Sons Inc, 2013-12)
One of the current standard approaches to the study of animal welfare is measuring hypothalamic-pituitary-adrenal activity, frequently in association with behavioral assessment. We studied the effects of food-based ...