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A Computational Approach From Gene to Structure Analysis of the Human ABCA4 Transporter Involved in Genetic Retinal Diseases.
(Association For Research In Vision And Ophthalmology, 2018)
ER stress is associated with reduced ABCA-1 protein levels in macrophages treated with advanced glycated albumin - Reversal by a chemical chaperone
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2012)
ATP-binding cassette transporter A1 mediates the export of excess cholesterol from macrophages, contributing to the prevention of atherosclerosis. Advanced glycated albumin (AGE-alb) is prevalent in diabetes mellitus and ...
Inhibition of Macrophage Oxidative Stress Prevents the Reduction of ABCA-1 Transporter Induced by Advanced Glycated Albumin
(SPRINGER HEIDELBERGHEIDELBERG, 2012)
We investigated the role of aminoguanidine and benfotiamine on the inhibition of reactive oxygen species (ROS) generation in macrophages induced by advanced glycated albumin (AGE-albumin) and its relationship with cell ...
ABCA1 expression and statins: inhibitory effect in peripheral blood mononuclear cells
(FUTURE MEDICINE LTD, 2009)
The ATP-binding cassette transporter A1 (ABCA1) has an essential role in the formation of nascent high-density lipoprotein particles and also participates in the cholesterol efflux from macrophages in the artery wall. ...
Evidence of ABCA1-mediated cholesterol efflux from mouse oocytes to HDL.
(2017)
Membrane cholesterol transporters such as ABCA1 and ABCG1 mediate the efflux of this lipid from cells to HDL. HDL cholesterol is taken up in the liver by Scavenger Receptor Class B type I (SR-BI) and subsequently metabolized ...
Ovarian reverse cholesterol transport: contribution of follicular fluid HDL and ABCA1 transporter to mouse oocyte cholesterol homeostasis
(2017)
Cholesterol efflux from cells to high density lipoproteins (HDL) is mediated by membrane transporters such as ATP-Binding Cassette transporter A1 (ABCA1) and ABCG1. HDL cholesterol is taken up by liver Scavenger receptor ...
Papel de ABCA1 en el contenido de colesterol de membrana y en el transporte de glucosa mediada por GLUT4 en fibras musculares de ratones adultos
(Universidad de Chile, 2017)
El transportador ATP Binding Cassette A1 (ABCA1) facilita el flujo de salida de colesterol hacia las apolipoproteinas A-1 (apoA-1) libre de lípidos, siendo una proteína de membrana esencial en las etapas iniciales de la ...
Relationship between SLCO1B(3) and ABCA(3) polymorphisms and imatinib response in chronic myeloid leukemia patients
(Maney Publishing, 2015-04-01)
Background: Genetic variations in membrane transporters may contribute to imatinib mesylate (IM) resistance in chronic myeloid leukemia (CML).Objective: To investigate the relationship between SLCO1B3, SLCO1A2, and ABCA3 ...
Role of plasma and liver cholesterol- and lipoprotein-metabolism determinants in LpX formation in the mouse
(ELSEVIER SCIENCE BV, 2007)
Cholestasis is characterized by hypercholesterolemia and the appearance of an abnormal lipoprotein, lipoprotein X (LpX), in plasma. The mechanisms responsible for this cholestatic plasma lipid phenotype are not fully ...