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Derivados del colesterol en el alga roja Laurencia papillosa (Forssk.) Grev.
(1991)
La gran mayoría de las algas de la división Rhodophyta contienen colesterol como el contribuye esteroidal C27 mayoritario a pesar de que en algunas especies el desmosterol es el que se encuentra en cantidades apreciables, ...
Synthesis and antiviral activity of sulfated and acetylated derivatives of 2β,3α-dihydroxy-5α-cholestane
(Elsevier Science Inc, 2003-02)
Five new steroid sulfates, sodium 2β,3α-dihydroxy-5α-cholestane 3-sulfate (6), sodium 2β,3α-dihydroxy-5α-cholestane 2-sulfate (7), disodium 2β,3α-dihydroxy-5α-cholestane disulfate (8), sodium 3α-acetoxy-2β-hydroxy-5α-cholestane ...
Polyhydroxylated sulfated steroids derived from 5α-cholestanes as antiviral agents against herpes simplex virus
(Springer Wien, 2016-07)
Twelve polyhydroxylated sulfated steroids synthesized from a 5α-cholestane skeleton with different substitutions in C-2, C-3 and C-6 were evaluated for cytotoxicity and antiviral activity against herpes simplex virus (HSV) ...
Synthesis and cytotoxic evaluation of four new 6E-hydroximinosteroids
(Elsevier, 2014-03-13)
Four new 6E-hydroximinosteroids (1, 2a, 3 and 4) have been synthesized from the corresponding ketones, 2β,3β-dihydroxy-5α-cholestan-6-one (5), 2α,3α-dihydroxy-5α-cholestan-6-one (6), 2β,3α-dihydroxy-5α-cholestan-6-one (7) ...
Synthesis and acetylcholinesterase inhibitory activity of polyhydroxylated sulfated steroids: structure/activity studies
(Elsevier, 2013-08)
Disulfated and trisulfated steroids have been synthesized from cholesterol and their acetylcholinesterase inhibitory activity has been evaluated. In our studies we have found that the activity was not only dependent on the ...
Topography of nicotinic acetylcholine receptor membrane-embedded domains
(American Society for Biochemistry and Molecular Biology, 2000-12)
The topography of nicotinic acetylcholine receptor (AChR) membrane-embedded domains and the relative affinity of lipids for these protein regions were studied using fluorescence methods. Intact Torpedo californica AChR ...