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Identification of antioxidant peptides of hen egg-white lysozyme and evaluation of inhibition of lipid peroxidation and cytotoxicity in the Zebrafish model
(Springer, 2016-04-01)
Hen egg lysozyme was hydrolyzed with pepsin in situ on a cation-exchange column to isolate antioxidant peptides. The most cationic fraction was eluted with 1 M NaCl. Five positively charged peptides f(109–119) VAWRNRCKGTD, ...
Analytical method for determination of nitric oxide in zebrafish larvae: Toxicological and pharmacological applications
(ACADEMIC PRESS INC ELSEVIER SCIENCESAN DIEGO, 2012-02-15)
Zebrafish are currently used at various stages of the drug discovery process and can be a useful and cost-effective alternative to some mammalian models. Nitric oxide (NO) plays an important role in physiology of zebrafish. ...
Optimization and Pharmacological Validation of a Leukocyte Migration Assay in Zebrafish Larvae for the Rapid In Vivo Bioactivity Analysis of Anti-Inflammatory Secondary Metabolites
(2013-10-04)
Over the past decade, zebrafish (Danio rerio) have emerged as an attractive model for in vivo drug discovery. In this study, we explore the suitability of zebrafish larvae to rapidly evaluate the anti-inflammatory activity ...
Digestibility of Quinoa (Chenopodium quinoa Willd.) Protein Concentrate and Its Potential to Inhibit Lipid Peroxidation in the Zebrafish Larvae Model
(Springer, 2017-09)
Quinoa protein concentrate (QPC) was extracted and digested under in vitro gastrointestinal conditions. The protein content of QPC was in the range between 52.40 and 65.01% depending on the assay used. Quinoa proteins were ...
Live-cell imaging of Salmonella Typhimurium interaction with zebrafish larvae after injection and immersion delivery methods
(Elsevier B.V., 2017)
© 2017The zebrafish model has been used to determine the role of vertebrate innate immunity during bacterial infections. Here, we compare the in vivo immune response induced by GFP-tagged Salmonella Typhimurium inoculated ...
Antiangiogenic, antimigratory and antiinflammatory effects of 2-methoxyestradiol in zebrafish larvae
(SPRINGER, 2013)
2-Methoxyestradiol (2ME), an endogenous metabolite of 17 beta-estradiol, has been previously reported to possess antiangiogenic and antitumor properties. Herein, we demonstrate that the effects of this antiangiogenic steroid ...
Resposta motora em larvas de Zebrafish expostas previamente à um tratamento crônico com dopamina
(Universidade Federal de Minas GeraisUFMG, 2016-09-30)
The early stages of neurodevelopment are crucial to the normal development of the brain. Alterations during neurodevelopment can lead to behavioral and physiological alterations in adult life, which can be associated to ...
Potential probiotic yeasts isolated from the fish gut protect zebrafish (Danio rerio) from a Vibrio anguillarum challenge
(Frontiers Media, 2015)
Due to the negative consequences associated with the use of antibiotics, researchers, and food producers have studied alternatives, such as probiotics, for the control of fish diseases. The probiotic properties of yeasts ...