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Functional assessment of SLC4A11, an integral membrane protein mutated in corneal dystrophies
(American Physiological Society, 2016-08)
SLC4A11, a member of the SLC4 family of bicarbonate transporters, is a widely expressed integral membrane protein, abundant in kidney and cornea. Mutations of SLC4A11 cause some cases of the blinding corneal dystrophies, ...
A biochemical framework for SLC4A11, the plasma membrane protein defective in corneal dystrophies
(American Chemical Society, 2011-03)
Mutations in the SLC4A11 protein, reported as a sodium-coupled borate transporter of the human plasma membrane, are responsible for three corneal dystrophies (CD): congenital hereditary endothelial dystrophy type 2, Harboyan ...
Renal and non-renal response of ABC and SLC transporters in chronic kidney disease
(Informa Healthcare, 2021-05)
Introduction: The solute carrier (SLC) and the ATP-binding cassette (ABC) transporter superfamilies play essential roles in the disposition of small molecules (endogenous metabolites, uremic toxins, drugs) in the blood, ...
Evidence of endometrial amino acid metabolism and transport modulation by peri-ovulatory endocrine profiles driving uterine receptivity
(BioMed Central, 2017)
Abstract
Background
In beef cattle, changes in the periovulatory endocrine milieu are associated with fertility and conceptus growth. A large preovulatory follicle (POF) ...
Decreased Expression of the Human Urea Transporter SLC14A1 in Bone is Induced by Cytokines and Stimulates Adipogenesis of Mesenchymal Progenitor Cells
(Johann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbh, 2020-09)
The human urea transporter SLC14A1 (HUT11/UT-B) has been suggested as a marker for the adipogenic differentiation of bone cells with a relevance for bone diseases. We investigated the function of SLC14A1 in different cells ...
Iron homeostasis in the lung
(Sociedad de Biología de Chile, 2006)
Cl−/HCO3− Exchanger slc26a6: a ph regulator shapes the cardiac action potential
(Lippincott Williams, 2017-10)
Regulation of intracellular pH (pHi) is often considered a ?housekeeping? function, contributing little to cardiac function. With the study published by Sirish et al7 in this issue of Circulation: Arrhythmia and ...
Genetic variants in the SLC16A11 gene are associated with increased BMI and insulin levels in nondiabetic Chilean population
(Archives of Endocrinology and Metabolism, 2021)