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La vía de señalización Rho/Rho-cinasa en la enfermedad y el remodelado cardiovascular
(EDICIONES DOYMA S/L, 2005)
The small guanosine triphosphatase Rho and its target, Rho kinase, play important roles in both blood pressure regulation and vascular smooth muscle contraction. Rho is activated by agonists of receptors coupled to cell ...
PYK2/PDZ-RhoGEF Links Ca(2+) Signaling to RhoA
(LIPPINCOTT WILLIAMS & WILKINS, 2009)
Objective-Ras homolog gene family member A (RhoA)/Rho-kinase-mediated Ca(2+) sensitization is a critical component of constrictor responses. The present study investigates how angiotensin II activates RhoA. Methods and ...
Investigação de vias de sinalização celular relacionadas às proteínas Rho GTPases RhoC e RhoA em leucemia mieloide aguda
(Universidade Federal de São Paulo, 2022-03)
A Leucemia Mieloide Aguda (LMA) é um grupo heterogêneo de neoplasias hematológicas que acomete principalmente idosos. Na LMA, a hematopoiese é desregulada e há acúmulo de células imaturas (blastos) na medula óssea e sangue ...
Multiple gene knock-down by a single lentiviral vector expressing an array of short hairpin RNAs
(Pontificia Universidad Católica de Valparaíso, 2006)
Mucor rouxii Rho1 protein; characterization and possible role in polarized growth
(Springer, 2007-04)
We have previously shown that protein kinase A of the medically important zygomycete Mucor rouxii participates in fungal morphology through cytoskeletal organization. As a first step towards finding the link between protein ...
Number of expressed cancer/testis antigens identifies focal adhesion pathway genes as possible targets for multiple myeloma therapy
(TAYLOR & FRANCIS LTD, 2010)
Considering that the importance of cancer/testis (CT) antigens in multiple myeloma (MM) biology is still under investigation, the present study aimed to: (1) identify genes differentially expressed in MM using microarray ...
Number of expressed cancer/testis antigens identifies focal adhesion pathway genes as possible targets for multiple myeloma therapy
(Taylor & Francis Ltd, 2010-08-01)
Considering that the importance of cancer/testis (CT) antigens in multiple myeloma (MM) biology is still under investigation, the present study aimed to: (1) identify genes differentially expressed in MM using microarray ...
Detection of changes in mould cell wall stress-related gene expression by a novel reverse transcription real-time PCR method
(Elsevier Science, 2018-06)
The cell wall integrity (CWI) pathway is activated in response to cell wall stresses due to different food-related environments. Rho1 is one of the main regulators within such pathway. The objective of this work was to ...