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Subcellular movement of signaling molecules: how and why?
(Nova Science Publishers, 2006)
The biological function of proteins is determined by their cellular localization and subsequent interactions with other factors within a given subcellular compartment. Therefore, it is critical to understand how proteins ...
Retrograde transport of the GR requires dynamic assembly of complexes with hsp90 and is linked to the CHIP component of the proteosome
(Elsevier, 2004-12)
Here, we have used a chimera of green fluorescent protein (GFP) and the glucocorticoid receptor (GR) to study retrograde movement of a model soluble (i.e., non-vesicle-associated) protein in axons and dendrites of cultured ...
Alternative pathways for catecholamine action in oral motor control
(Elsevier B.V., 2005-09-01)
Orofacial movement is a complex function performed by facial and jaw muscles. Jaw movement is enacted through the triggering of motoneurons located primarily in the trigeminal motor nucleus (Mo5). The Mo5 is located in the ...
Alternative pathways for catecholamine action in oral motor control
(Elsevier B.V., 2005-09-01)
Orofacial movement is a complex function performed by facial and jaw muscles. Jaw movement is enacted through the triggering of motoneurons located primarily in the trigeminal motor nucleus (Mo5). The Mo5 is located in the ...
Alternative pathways for catecholamine action in oral motor control
(Elsevier B.V., 2014)
Evidence for glucocorticoid receptor transport on microtubules by dynein
(American Society for Biochemistry and Molecular Biology, 2004)
Rapid, ligand-dependent movement of glucocorticoid receptors (GR) from cytoplasm to the nucleus is hsp90-dependent, and much of the movement system has been defined. GR.hsp90 heterocomplexes isolated from cells contain one ...
Role of hsp90 and the hsp90-binding immunophilins in signalling protein movement
(Elsevier Inc, 2004)
The ubiquitous protein chaperone hsp90 has been shown to regulate more than 100 proteins involved in cellular signalling. These proteins are called 'client proteins' for hsp90, and a multiprotein hsp90/hsp70-based chaperone ...
Cyclophilin-A is bound to through its peptidylprolyl isomerase domain to the cytoplasmic dynein motor protein complex
(American Society for Biochemistry and Molecular Biology, 2004-10-20)
Although cyclophilin A (CyP-A) is a relatively abundant small immunophilin present in the cytoplasm of all mammalian cells, its general function(s) in the absence of the immunosuppressant drug cyclosporin A is not known. ...
Escola sem Partido: ideologia e discurso
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Educação - PPGECâmpus São Carlos, 2022-07-22)
In the past few years, the self-styled No Party School Movement (MESP) and their discourses have risen throughout the Brazilian scene. It is understood that the MESP has the potential to cause drastic and at the same time ...