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The long-lasting sensitization of primary afferent nociceptors induced by inflammation involves prostanoid and dopaminergic systems in mice
(Pharmacology Biochemistry and Behavior, 2013)
K-ATP(+) Channels-Independent Analgesic Action of Crotalus durissus cumanensis venom
(Natural Products Inc, 2010-07-01)
The effect was investigated of the K+ channel blocker, glibenclamide, on the ability of Crotalus durissus cumanensis venom (CDCM) to promote peripheral antinociception. This was measured by formalin-induced nociception in ...
K-ATP(+) Channels-Independent Analgesic Action of Crotalus durissus cumanensis venom
(Natural Products Inc, 2010-07-01)
The effect was investigated of the K+ channel blocker, glibenclamide, on the ability of Crotalus durissus cumanensis venom (CDCM) to promote peripheral antinociception. This was measured by formalin-induced nociception in ...
K+ATP channels-independent analgesic action of Crotalus durissus cumanensis venom
(2010-01-01)
The effect was investigated of the K+ channel blocker, glibenclamide, on the ability of Crotalus durissus cumanensis venom (CDCM) to promote peripheral antinociception. This was measured by formalin-induced nociception in ...
Genetic components of human pain sensitivity: A protocol for a genome-wide association study of experimental pain in healthy volunteers
(BMJ Publishing Group, 2019)
INTRODUCTION: Pain constitutes a major component of the global burden of diseases. Recent studies suggest a strong genetic contribution to pain susceptibility and severity. Whereas most of the available evidence relies on ...
Oxytocin Modulates Nociception as an Agonist of Pain-Sensing TRPV1
(2017)
Oxytocin is a hormone with various actions. Oxytocin-containing parvocellular neurons project to the brainstem and spinal cord. Oxytocin release from these neurons suppresses nociception of inflammatory pain, the molecular ...
Contribution of peripheral vanilloid receptor to the nociception induced by injection of spermine in mice
(PERGAMON-ELSEVIER SCIENCE LTD, 2011)
Polyamines (putrescine, spermidine and spermine) are important endogenous regulators of ion channels, such as vanilloid (TRPV1), glutamatergic (NMDA or AMPA/kainate) and acid-sensitive (ASIC) receptors. In the present ...
The long-lasting sensitization of primary afferent nociceptors induced by inflammation involves prostanoid and dopaminergic systems in mice
(Pharmacology Biochemistry and Behavior, 2013)
In recent years, evidence that sensitization of primary afferent nociceptors is an important event associated with chronic pain has been accumulating. The present study aimed to evaluate the participation of the prostaglandin ...
Nerve growth factor acts with the beta 2-adrenoceptor to induce spontaneous nociceptive behavior during temporomandibular joint inflammatory hyperalgesia
(Pergamon-elsevier Science LtdOxfordInglaterra, 2008)