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Polymorphism of the Human Immunodeficiency Virus Type 1 in Brazil: Genetic Characterization of the nef Gene and Implications for Vaccine Design
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz., 2020)
Genetic and Functional Analysis of HIV Type 1 nef Gene Derived from Long-Term Nonprogressor Children: Association of Attenuated Variants with Slow Progression to Pediatric AIDS
(Mary Ann Liebert, 2012-11)
Among persons infected by HIV-1, the rate of progression to AIDS is multifactorial being affected by host and viral factors, including the HIV-encoded negative factor (Nef). Our aim was to define whether variations in the ...
Intrahost and Interhost Variability of the HIV Type 1 nef Gene in Brazilian Children
(Mary Ann Liebert Inc, 2009-11-01)
Many aspects of HIV-1 pathogenesis are affected by Nef protein activity, and efforts have been made to study variation in the nef gene and how that variation relates to disease outcome. We studied the genetic diversity of ...
Variants in the CYP7B1 gene region do not affect natural resistance to HIV-1 infection
(BMC (Biomed Central)InmunovirologíaLondres, Inglaterra, 2022)
Análise da diversidade genética no gene nef do vírus da imunodeficiência humana do tipo 1(HIV-1) em crianças e em adultos recém infectados
(Universidade Federal de São Paulo (UNIFESP), 2007)
Diversos estudos clínicos têm demonstrado que a dinâmica da AIDS na infecção pediátrica difere da observada em adultos. Em especial, diferenças na carga viral, taxa de depleção de linfócitos e rapidez no aparecimento dos ...
Polymorphism of the Human Immunodeficiency Virus Type 1 in Brazil: Genetic Characterization of the nef Gene and Implications for Vaccine Design
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz., 2002)