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Proteomic and metabolomic characterization of COVID-19 patient sera
Early detection and effective treatment of severe COVID-19 patients remain major challenges. Here, we performed proteomic and metabolomic profiling of sera from 46 COVID-19 and 53 control individuals. We then
trained a ...
Exploratory analysis using MRM profiling mass spectrometry of a candidate metabolomics sample for testing system suitability
(2021-10-01)
Multiple reaction monitoring (MRM) profiling is an exploratory mass spectrometry (MS) method applicable to the initial screening of complex samples for small molecules based on their chemical functionalities. We report on ...
Genomics, proteomics and metabolomics: Their emerging roles in the discovery and validation of rheumatoid arthritis biomarkers
(Clinical and Experimental Rheumatology S.A.S., 2015)
Metabolomics for predicting hyperglycemia in pregnancy: A protocol for a systematic review and potential meta-analysis
(2019-08-24)
Background: Hyperglycemia in pregnancy (HIP) has been recently differentiated between diabetes in pregnancy (DIP) and gestational diabetes mellitus (GDM). The proposed protocol is relevant, and clinical concern is due to ...
Carbohydrate tolerance in Amazon tambaqui (Colossoma macropomum) revealed by NMR-metabolomics - Are glucose and fructose different sugars for fruit-eating fish?
(2022-03-01)
In the present study, two approaches were followed to evaluate the metabolic responses of tambaqui (Colossoma macropomum), a frugivorous species, to intraperitoneal (IP) administration of glucose (GLU) and fructose (FRU) ...
Making Sense Of Blood-based Proteomics And Metabolomics In Psychiatric Research
(Oxford Univ PressOxford, 2016)
Metabolomics and Machine Learning Approaches Combined in Pursuit for More Accurate Paracoccidioidomycosis Diagnoses
(Amer Soc Microbiology, 2020-05-01)
Brazil and many other Latin American countries are areas of endemicity for different neglected diseases, and the fungal infection paracoccidioidomycosis (PCM) is one of them. Among the clinical manifestations, pneumopathy ...
Metabolomics and machine learning approaches combined in pursuit for more accurate paracoccidioidomycosis diagnoses
(2020-06-01)
Brazil and many other Latin American countries are areas of endemicity for different neglected diseases, and the fungal infection paracoccidioidomycosis (PCM) is one of them. Among the clinical manifestations, pneumopathy ...
Discovery of food identity markers by metabolomics and machine learning technology
(Nature Publishing Group, 2019-12)
Verification of food authenticity establishes consumer trust in food ingredients and components of processed food. Next to genetic or protein markers, chemicals are unique identifiers of food components. Non-targeted ...