Buscar
Mostrando ítems 1-10 de 39
A novel mutation in the TPO gene in goitrous hypothyroid patients with iodide organification defect
(Blackwell Science LtdOxfordInglaterra, 1999)
Autoimmunity does not contribute to the highly prevalent glucose metabolism disturbances in a Japanese Brazilian population
(2007-12-01)
The Japanese Brazilian population has one of the highest prevalences of diabetes worldwide. Despite being non-obese according to standard definitions, their body fat distribution is typically central. We investigated whether ...
Autoimmunity does not contribute to the highly prevalent glucose metabolism disturbances in a Japanese Brazilian population
(2007-12-01)
The Japanese Brazilian population has one of the highest prevalences of diabetes worldwide. Despite being non-obese according to standard definitions, their body fat distribution is typically central. We investigated whether ...
Congenital goitrous hypothyroidism: mutation analysis in the thyroid peroxidase gene
(Wiley Blackwell Publishing, Inc, 2012-04)
Background: Iodide organification defect (IOD) is characterized by a reduced ability of the thyroid gland to retain iodide resulting in hypothyroidism. Mutations in thyroid peroxidase (TPO) gene appear to be the most common ...
Comparative effects of transforming growth factor beta isoforms on redox metabolism in thyroid cells
(Elsevier Ireland, 2017-10)
Introduction: Transforming growth factor beta (TGF-β) regulates thyroid function and growth. However, tumoral thyroid cells became resistant to this factor as they undifferentiated. Little is known about the effects of ...
Lack of in vitro effect of antithyroid drugs upon peroxidase antigen expression in autoimmune thyroid disease Ausencia de efecto in vitro de las drogas antitiroideas sobre la expresion del antigeno peroxidasa en las enfermedades autoinmunes del tiroides.
(1993)
The aim of this study is to determine whether antithyroid drugs (ATD) act via inhibiting thyroid hormone synthesis or by interfering with the immune process which leads to autoimmune disease. Previously we had demonstrated ...
Autoimmune thyroid disease in euthyroid subjects
(Universidad del RosarioFacultad de medicina, 2018)
Five novel inactivating mutations in the thyroid peroxidase gene responsible for congenital goiter and iodide organification defect
(Veterinary and Human Toxicology, 2003-12)
Thyroid peroxidase (TPO) defects, typically transmitted as autosomal recessive traits, result in hypothyroid goiters with failure to convert iodide into organic iodine. We analyzed the TPO gene in 14 unrelated patients ...