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Effectiveness of commercial inhibitors against subtype F HIV-1 protease
(TAYLOR & FRANCIS LTD, 2009)
Subtype F wild type HIV protease has been kinetically characterized using six commercial inhibitors (amprenavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir) commonly used for HIV/AIDS treatment, as well as ...
Comparative molecular field analysis of a series of inhibitors of HIV-1 protease
(BENTHAM SCIENCE PUBL LTD, 2011)
Several protease inhibitors have reached the world market in the last fifteen years, dramatically improving the quality of life and life expectancy of millions of HIV-infected patients. In spite of the tremendous research ...
Pharmacokinetic Parameters of HIV-1 Protease Inhibitors
(2020-06-17)
Since the beginning of the HIV epidemic, research has been carried out to control the virus. Understanding the mechanisms of replication has given access to the various classes of drugs that over time have transformed AIDS ...
Oral candidiasis in HIV+ patients under treatment with protease inhibitors
(Sociedade Brasileira de Pesquisa Odontológica, 2008)
The purpose of this work was to evaluate the influence of Protease Inhibitors (PI) on the occurrence of oral candidiasis in 111 HIV+ patients under PI therapy (Group A). The controls consisted of 56 patients that were not ...
Alkyl Hydroxybenzoic Acid Derivatives that Inhibit HIV-1 Protease Dimerization
(Bentham Science Publ Ltd, 2012-09-01)
The therapeutic potential of gallic acid and its derivatives as anti-cancer, antimicrobial and antiviral agents is well known. We have examined the mechanism by which natural gallic acid and newly synthesized gallic acid ...
Alkyl Hydroxybenzoic Acid Derivatives that Inhibit HIV-1 Protease Dimerization
(Bentham Science Publ Ltd, 2012-09-01)
The therapeutic potential of gallic acid and its derivatives as anti-cancer, antimicrobial and antiviral agents is well known. We have examined the mechanism by which natural gallic acid and newly synthesized gallic acid ...