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An updated map of Trypanosoma cruzi histone post-translational modifications
(Nature Research, 2021)
Histone modifications related to chromosome silencing and elimination during male meiosis in Bengalese finch
(Springer Verlag Berlín, 2014-06)
We report here that a germline-restricted chromosome (GRC) is regularly present in males and females of the Bengalese finch (Lonchura domestica). While the GRC is euchromatic in oocytes, in spermatocytes this chromosome ...
Comparative effects of histone deacetylases inhibitors and resveratrol on Trypanosoma cruzi replication, differentiation, infectivity and gene expression
(Elsevier, 2017-04)
Histone post-translational modification, mediated by histone acetyltransferases and deacetylases, is one of the most studied factors affecting gene expression. Recent data showing differential histone acetylation states ...
Epigenetics in Inflammatory Breast Cancer: Biological Features and Therapeutic Perspectives
(2020-05-08)
Evidence has emerged implicating epigenetic alterations in inflammatory breast cancer (IBC) origin and progression. IBC is a rare and rapidly progressing disease, considered the most aggressive type of breast cancer (BC). ...
Implications of epigenetic modulation for novel treatment approaches in patients with schizophrenia
(Elsevier B.V., 2014-02-01)
Schizophrenia is a heterogeneous and complex mental disorder with high rates of disability, non-recovery, and relapse. the primary pharmacological treatments for schizophrenia are antipsychotics. Notwithstanding the efficacy ...
Histone methylations in the developing central nervous system and in neural tube defects
(De Gruyter, 2018-05)
Understanding central nervous system genesis is of crucial relevance to decode different human diseases such as microcephaly or neural tube defects, which arise from incorrect developmental processes. Epigenetic mechanisms ...
An integrative analysis of post-translational histone modifications in the marine diatom Phaeodactylum tricornutum
(BioMed Central, 2015)
Background:
Nucleosomes are the building blocks of chromatin where gene regulation takes place. Chromatin landscapes have been profiled for several species, providing insights into the fundamental mechanisms of ...
Heterogeneous distribution of histone methylation in mature human sperm
(Springer, 2014-01-31)
Purpose
To analyze the presence of various histone modifications in ejaculated human spermatozoa
Methods
In this prospective study, seminal ejaculates from 39 normozoospermic individuals were evaluated for semen analysis ...
Epigenetic modifications and their roles in animal reproduction.
(In: SENEDA , M. M.; SILVA-SANTOS, K. C.; MARINHO, L. S. R. (Ed.). Biotechnology of animal reproduction. New York: Nova Science Publishers, Inc., 2016. (Recent trends in biotechnology). p. 315-341., 2016)