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Synthetic tools for the characterization of galactofuranosyl transferases. Glycosylations via acylated glycosyl iodides
(Elsevier, 2013-06-07)
With the aim to develop synthetic tools for the characterization of galactofuranosyltransferases, the synthesis of 9-decenyl glycosides of D-Manp, D-Galf and beta-D-Galf-(1,3)-D-Manp was targeted. The interest in the alkenyl ...
The role of glycosyltransferases in colorectal cancer
(MDPI, 2021)
Colorectal cancer (CRC) is one of the main causes of cancer death in the world. Post-translational
modifications (PTMs) have been extensively studied in malignancies due to its relevance in
tumor pathogenesis and therapy. ...
Genomic Cloning and Sequence Analysis of Trypanosoma brucei rhodesiense gene Encoding Putative N-glycosylation Enzyme
(Universidade Federal do Rio Grande do Sul, 2018)
An acetylation site in lectin domain modulates the biological activity of polypeptide GalNAc-transferase-2
(De Gruyter, 2012-12)
Polypeptide GalNAc-transferases (ppGalNAc-Ts) are a family of enzymes that catalyze the initiation of mucintype O -glycosylation. All ppGalNAc-T family members contain a common (QXW) 3 motif, which is present in the R-type ...
N-Glycosylation in piroplasmids: diversity within simplicity
(Multidisciplinary Digital Publishing Institute, 2021-01)
N-glycosylation has remained mostly unexplored in Piroplasmida, an order of tick-transmitted pathogens of veterinary and medical relevance. Analysis of 11 piroplasmid genomes revealed three distinct scenarios regarding ...
N-Glycosylation in piroplasmids : Diversity within simplicity
(MDPI, 2021-01)
N-glycosylation has remained mostly unexplored in Piroplasmida, an order of tick-transmitted pathogens of veterinary and medical relevance. Analysis of 11 piroplasmid genomes revealed three distinct scenarios regarding ...
Core 1 O-N-acetylgalactosamine (O-GalNAc) glycosylation in the human cell nucleus
(De Gruyter, 2020-08)
Glycosylation is a very frequent post-translational modification in proteins, and the initiation of O-N-acetylgalactosamine (O-GalNAc) glycosylation has been recently described on relevant nuclear proteins. Here we evaluated ...