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Estudo da Interação com o DNA e Inibição da Atividade Topoisomerase I de Derivados Tiazacridínicos e Imidazacridínicos
(Universidade Federal de Pernambuco, 2015)
Inhibition of Taq DNA Polymerase and Human Topoisomerase I by Resveratrol Derivatives
(Bentham Science Publishers, 2017-05)
Background: DNA polymerases and topoisomerases are proteins that play a vital part in DNA metabolism such as replication, transcription, recombination, and chromosome segregation during mitosis. For this reason, these ...
New Spiro-acridines: Dna Interaction, Antiproliferative Activity And Inhibition Of Human Dna Topoisomerases
(Elsevier Science BVAmsterdam, 2016)
Prognostic markers of low-grade squamous intraepithelial lesions: the role of topoisomerase II alpha and active caspase-3
(I R O G Canada, Inc, 2008-01-01)
Purpose: To study the relationship between topoisomerase II alpha, active caspase-3 expressions and HPV DNA in uterine cervices with low-grade squamous intraepithelial lesions (LSIL). Methods: Forty women with LSIL and 32 ...
Antioxidant and antitopoisomerase activities in plant extracts of some Colombian flora from La Marcada Natural Regional Park
(Universidad de Costa Rica, 2011)
Determination of in vitro absorption in Caco-2 monolayers of anticancer Ru(II)-based complexes acting as dual human topoisomerase and PARP inhibitors
(Springer, 2019-02-01)
Due to their unique and versatile biochemical properties, ruthenium-based compounds have emerged as promising anticancer agents. Previous studies showed that three ruthenium(II) compounds: [Ru(pySH)(bipy)(dppb)]PF6 (1), ...