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Dexamethasone-induced muscular atrophy is mediated by functional expression of connexin-based hemichannels
(Elsevier, 2016)
Long-term treatment with high glucocorticoid doses induces skeletal muscle atrophy. However, the molecular mechanism of such atrophy remains unclear. We evaluated the possible involvement of connexin-based hemichannels (Cx ...
Dexamethasone-induced muscular atrophy is mediated by functional expression of connexin-based hemichannels
(2016)
Long-term treatment with high glucocorticoid doses induces skeletal muscle atrophy. However, the molecular mechanism of such atrophy remains unclear. We evaluated the possible involvement of connexin-based hemichannels (Cx ...
De novo expression of functional connexins 43 and 45 hemichannels increases sarcolemmal permeability of skeletal myofibers during endotoxemia
(2019)
Endotoxemia caused by bacterial lipopolysaccharides (LPSs) leads to severe skeletal muscular deterioration, starting with higher membrane permeability and decline in resting membrane potential (RMP). However, the molecular ...
Differential expression of the fractalkine chemokine receptor (CX3CR1) in human monocytes during differentiation
(Chinese Soc Immunology, 2014-12)
Circulating monocytes (Mos) may continuously repopulate macrophage (MAC) or dendritic cell (DC) populations to maintain homeostasis. MACs and DCs are specialized cells that play different and complementary immunological ...
High Bone Mass in Mice Lacking Cx37 Because of Defective Osteoclast Differentiation
(Amer Soc Biochemistry Molecular Biology Inc, 2014-03-21)
Background: Connexin proteins are essential for cell differentiation, function, and survival. Results: Global deletion of Cx37 results in increased bone mass caused by reduced osteoclast maturation. Conclusion: Our findings ...
Connexins in melanoma: Potential role of Cx46 in its aggressiveness
(2020-11)
Melanoma is the most aggressive skin cancer, and in metastatic advanced states,
it is completely refractory to chemotherapy. Therefore, it is relevant to understand
the molecular bases that rule their aggressiveness. ...