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Self-declared ethnicity and genomic ancestry in prostate cancer patients from Brazil
(Funpec-editora, 2016-01-01)
Some studies of polymorphisms in prostate cancer (PCa) analyze individuals in a uniform manner, regardless of genetic ancestry. However, PCa aggressiveness differs between subjects of African descent and those of European ...
Gallbladder Cancer Risk and Indigenous South American Mapuche Ancestry: Instrumental Variable Analysis Using Ancestry-Informative Markers
(MDPI, 2023)
A strong association between the proportion of indigenous South American Mapuche ancestry and the risk of gallbladder cancer (GBC) has been reported in observational studies. Chileans show the highest incidence of GBC ...
Development of a panel of genome-wide ancestry informative markers to study admixture throughout the americas
(Public Library of Science, 2012)
Most individuals throughout the Americas are admixed descendants of Native American, European, and African ancestors. Complex historical factors have resulted in varying proportions of ancestral contributions between ...
Revisiting the Genetic Ancestry of Brazilians Using Autosomal AIM-Indels
(Public Library of Science, 2016)
A minimum set of ancestry informative markers for determining admixture proportions in a mixed American population: the Brazilian set
(European Society of Human GeneticsBrasil, 2015-09)
The Brazilian population is considered to be highly admixed. The main contributing ancestral populations were European and African, with Amerindians contributing to a lesser extent. The aims of this study were to provide ...
Neither self-reported ethnicity nor declared family origin are reliable indicators of genomic ancestry
(2016-06-01)
Ancestry information can be useful in investigations of diseases with a genetic or infectious background. As the Brazilian population is highly admixed physical traits tend to be poor indicators of ancestry. The assessment ...
Ancestry informative markers and selected single nucleotide polymorphisms in immunoregulatory genes on preterm labor and preterm premature rupture of membranes: A case control study
(2016-02-05)
Background: A genetic predisposition to Preterm Labor (PTL) and Preterm Premature Rupture of Membranes (PPROM) has been suggested; however the relevance of polymorphisms and ancestry to susceptibility to PTL and PPROM in ...
Assessing Individual Interethnic Admixture and Population Substructure Using a 48-Insertion-Deletion (INSEL) Ancestry-Informative Marker (AIM) Panel
(WILEY-LISS, 2010)
Estimating the proportions of different ancestries in admixed populations is very important in population genetics studies, and it is particularly important for detecting population substructure effects in case-control ...