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Induction of Indoleamine 2,3-Dioxygenase by Gene Delivery in Allogeneic Islets Prolongs Allograft Survival
(WILEY-BLACKWELL, 2010)
Indoleamine 2,3-dioxygenase (IDO), an enzyme that plays a critical role in fetomaternal tolerance, exerts immunoregulatory functions suppressing T-cell responses. The aims of this study were to promote IDO expression in ...
ALLOGENEIC TRANSPLANTATION WITH BLOOD STEM-CELLS MOBILIZED BY RHG-CSF FOR HEMATOLOGICAL MALIGNANCIES
(Stockton PressBasingstokeInglaterra, 1995)
Alloreactive regulatory T cells generated with retinoic acid prevent skin allograft rejection
(Wiley-Blackwell, 2015)
CD4+CD25+Foxp3+ regulatory T (Treg) cells mediate immunological self-tolerance and
suppress immune responses. Retinoic acid (RA), a natural metabolite of vitamin A, has
been reported to enhance the differentiation of ...
Prospective analysis between the therapy of immunosuppressive medication and allogeneic microchimerism after liver transplantation
(ELSEVIER SCIENCE BV, 2009)
After liver transplantation, migration of donor-derived hematopoietic cells to recipient can be detected in pheripheral blood. This state is termed microchimerism. The aim of this study was to investigate prospectively the ...
Exogenous interleukin-33 targets myeloid-derived suppressor cells and generates periphery-induced Foxp3+ regulatory T cells in skin-transplanted mice
(Blackwell Publishing Ltd, 2015)
© 2015 John Wiley & Sons Ltd. Interleukin-33 (IL-33) has been a focus of study because of its variety of functions shaping CD4+ T-cell biology. In the present work, we evaluated the modulatory effect of IL-33 on suppressor ...
Allogeneic apoptotic thymocyte-stimulated dendritic cells expand functional regulatory T cells
(WILEY-BLACKWELL, 2011)
P>Dendritic cells (DCs) play an important role in the clearance of apoptotic cells. The removal of apoptotic cells leads to peripheral tolerance, although their role is still not clear. We show that the uptake of apoptotic ...
Expansion of CD4(+) CD25(+) Foxp3(+) T cells by bone marrow-derived dendritic cells
(WILEY-BLACKWELL PUBLISHING, INC, 2009)
Dendritic cells (DCs) are the most important antigen-presenting cells of the immune system and have a crucial role in T-lymphocyte activation and adaptive immunity initiation. However, DCs have also been implicated in ...
Current Status of Allograft Tolerance in Intestinal Transplantation
(Taylor & Francis, 2014-05)
Solid organ transplantation has become a clinical practice after the development of different immunosuppressive drugs that allowed controlling rejection. The price to be paid for that is the permanent risk of infections ...