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Hypercapnia-induced active expiration increases in sleep and enhances ventilation in unanaesthetized rats
(2018-08-01)
Key points: Expiratory muscles (abdominal and thoracic) can be recruited when respiratory drive increases under conditions of increased respiratory demand such as hypercapnia. Studying hypercapnia-induced active expiration ...
Generation of active expiration by serotoninergic mechanisms of the ventral medulla of rats
(2016-11-01)
Abdominal expiratory activity is absent at rest and is evoked during metabolic challenges, such as hypercapnia and hypoxia, or after the exposure to intermittent hypoxia (IH). The mechanisms engaged during this process are ...
Differential modulation of active expiration during hypercapnia by the medullary raphe in unanesthetized rats
(2020-11-01)
Active expiration represents an important mechanism to improve ventilation in conditions of augmented ventilatory demand, such as hypercapnia. While a rostral ventromedullary region, the parafacial respiratory group (pFRG), ...
Inhibitory control of active expiration by the Bötzinger complex in rats
(2020-01-01)
Key points: Contraction of abdominal muscles at the end of expiration during metabolic challenges (such as hypercapnia and hypoxia) improves pulmonary ventilation. The emergence of this active expiratory pattern requires ...
THE KOLLIKER-FUSE NUCLEUS ACTS AS A TIMEKEEPER FOR LATE-EXPIRATORY ABDOMINAL ACTIVITY
(Elsevier B.V., 2017-04-21)
While the transition from the inspiratory to the post-inspiratory (post-I) phase is dependent on the pons, little attention has been paid to understanding the role of the pontine respiratory nuclei, specifically the Kolliker ...
Active expiration and sympathetic excitation during hypercapnia require glutamatergic neurotransmission in the retrotrapezoid nucleus
(Federation Amer Soc Exp Biol, 2016-04-01)
Inhibitory control of active expiration by the Kolliker-Fuse in rats
(Federation Amer Soc Exp Biol, 2016-04-01)
Long-term facilitation of expiratory and sympathetic activities following acute intermittent hypoxia in rats
(2016-07-01)
Aim: Acute intermittent hypoxia (AIH) promotes persistent increases in ventilation and sympathetic activity, referred as long-term facilitation (LTF). Augmented inspiratory activity is suggested as a major component of ...
Vagal afferent control of abdominal expiratory activity in response to hypoxia and hypercapnia in rats
(Elsevier B.V., 2014-11-01)
In the present study, we tested the hypothesis that vagal afferent information modulates the pattern of expiratory response to hypercapnia and hypoxia. Simultaneous recordings of airflow, diaphragmatic (DIA) and oblique ...
Acute intermittent hypoxia evokes ventilatory long-term facilitation and active expiration in unanesthetized rats
(2021-12-01)
Acute intermittent hypoxia (AIH) modifies the functioning of the respiratory network, causing respiratory motor facilitation in anesthetized animals and a compensatory increase in pulmonary ventilation in freely behaving ...