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A Computational Approach From Gene to Structure Analysis of the Human ABCA4 Transporter Involved in Genetic Retinal Diseases.
(Association For Research In Vision And Ophthalmology, 2018)
ABCA1 expression and statins: inhibitory effect in peripheral blood mononuclear cells
(FUTURE MEDICINE LTD, 2009)
The ATP-binding cassette transporter A1 (ABCA1) has an essential role in the formation of nascent high-density lipoprotein particles and also participates in the cholesterol efflux from macrophages in the artery wall. ...
Inhibition of Macrophage Oxidative Stress Prevents the Reduction of ABCA-1 Transporter Induced by Advanced Glycated Albumin
(SPRINGER HEIDELBERGHEIDELBERG, 2012)
We investigated the role of aminoguanidine and benfotiamine on the inhibition of reactive oxygen species (ROS) generation in macrophages induced by advanced glycated albumin (AGE-albumin) and its relationship with cell ...
ER stress is associated with reduced ABCA-1 protein levels in macrophages treated with advanced glycated albumin - Reversal by a chemical chaperone
(PERGAMON-ELSEVIER SCIENCE LTDOXFORD, 2012)
ATP-binding cassette transporter A1 mediates the export of excess cholesterol from macrophages, contributing to the prevention of atherosclerosis. Advanced glycated albumin (AGE-alb) is prevalent in diabetes mellitus and ...
Effects of ABCA1 SNPs, including the C-105T novel variant, on serum lipids of Brazilian individuals
(ELSEVIER SCIENCE BV, 2008)
Background: ABCA1 plays an important role in HDL metabolism. Single nucleotide polymorphisms (SNPs) in ABCA1 gene were associated with variation in plasina HDL-c. Methods: The effect of the ABCA1 SNPs C-14T, R219K and of ...
Evidence of ABCA1-mediated cholesterol efflux from mouse oocytes to HDL.
(2017)
Membrane cholesterol transporters such as ABCA1 and ABCG1 mediate the efflux of this lipid from cells to HDL. HDL cholesterol is taken up in the liver by Scavenger Receptor Class B type I (SR-BI) and subsequently metabolized ...
Clinical and Genetic Spectrum of Stargardt Disease in Argentinean Patients
(Frontiers Media, 2021-03)
Purpose: To describe the clinical and molecular spectrum of Stargardt disease (STGD) in a cohort of Argentinean patients. Methods: This retrospective study included 132 subjects comprising 95 probands clinically diagnosed ...
Ethnicity of pathogenic variants in the ABCA4 gene: analysis of allele frequency in the general population
(Association for Research in Vision and Ophthalmology, 2020)
Papel de ABCA1 en el contenido de colesterol de membrana y en el transporte de glucosa mediada por GLUT4 en fibras musculares de ratones adultos
(Universidad de Chile, 2017)
El transportador ATP Binding Cassette A1 (ABCA1) facilita el flujo de salida de colesterol hacia las apolipoproteinas A-1 (apoA-1) libre de lípidos, siendo una proteína de membrana esencial en las etapas iniciales de la ...