Ausência de arteriosclerose na porção intramiocárdica das artérias coronárias: Um mistério a ser resolvido?
Brazilian Journal of Cardiovascular Surgery, v. 26, n. 3, p. 440-446, 2011.
Ramalli Jr, Edvaldo Luiz
Braga, Leonardo Henrique
Evora, Patricia Martinez
Albuquerque, Agnes Afrodite Sumarelli
Celotto, Andrea Carla
Mota, André Lupp
Evora, Paulo Roberto Barbosa
Several studies show that portions of intramyocardial coronary arteries are spared of arteriosclerosis, involving morphological, embryological, biochemical and pathophysiological aspects. Endothelial function is significantly affected in the segment of transition, as estimated by the vasoactive response to Ach. These findings suggest that myocardial bridge can provide protection against arteriosclerosis by counteracting the negative effects of endothelial dysfunction. The intramyocardial portion's protection phenomenon deserves further scientific research on all research fronts. Improved morphological, biomechanical and especially physiological and embryological knowledge may be the key to a future window of opportunity for chronic arterial disease therapy and prevention. In addition, this review discusses possible therapeutic approaches for symptomatic coronary ischemia caused by myocardial bridges.
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Ausência de arteriosclerose na porção intramiocárdica das artérias coronárias: Um mistério a ser resolvido? Universidade de São Paulo (USP); Universidade Estadual Paulista (UNESP); Laboratory of Vascular Reactivity and Endothelial Function; Laboratory of Biomedical Vascular Reactivity and Endothelial Function; Universidade de São (2011-07-01)Several studies show that portions of intramyocardial coronary arteries are spared of arteriosclerosis, involving morphological, embryological, biochemical and pathophysiological aspects. Endothelial function is significantly ...
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