Refining the intestinal motility test in mice to reduce animal stress
Revista de Ciencias Farmaceuticas, v. 24, n. 1, p. 79-82, 2003.
Marona, H. R N
Lucchesi, M. B B
A new protocol using 3-h fast animal for intestinal motility test was developed in our laboratory aiming the 3R's concept to reduce the stress of animals. Our results may aid in formulating recommendations that can be included in revised guidelines with regard to fasting time of mice.