Otro
Fluoride dose response in pH-cycling models using bovine enamel
Registro en:
Caries Research. Basel: Karger, v. 39, n. 6, p. 514-520, 2005.
0008-6568
10.1159/000088189
WOS:000232875100012
0000-0002-8159-4853
Autor
Vieira, AED
Delbem, ACB
Sassaki, K. T.
Rodrigues, E.
Cury, J. A.
Cunha, Robson Frederico
Resumen
The aim of this study was to establish methodologies for verification of the fluoride solution dose-response relationship using bovine enamel and pH-cycling models. Six models of the cariogenic challenge were performed, varying the time of demineralization and pH, time of remineralization, composition of de- and remineralization solutions, frequency and time of application of treatment solutions and pH-cycling duration. For the evaluation of the fluoride effect on caries dynamics, two proposed models provided for improvement in standardization of methods leading to a higher level of precision, demonstrating a dose response between treatments with regard to surface microhardness and Delta Z. For the evaluation of the fluoride effect on enamel remineralization, the addition of fluoride to the de- and remineralization solutions and the reduction of frequency and time of application of fluoride solutions led to a more suitable pH-cycling model. Copyright (C) 2005 S. Karger AG, Basel.
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