Artículos de revistas
Standardised Outcomes in Nephrology - Chronic Kidney Disease (SONG-CKD): a protocol for establishing a core outcome set for adults with chronic kidney disease who do not require kidney replacement therapy
Fecha
2021Registro en:
Trials (2021) 22:612
10.1186/s13063-021-05574-1
Autor
Evangelidis, Nicole
Sautenet, Benedicte
Madero, Magdalena
Tong, Allison
Ashuntantang, Gloria
Cortés Sanabria, Laura
de Boer, Ian H.
Fung, Samuel
Gallego, Daniel
Levey, Andrew S.
Levin, Adeera
Lorca, Eduardo
Okpechi, Ikechi G.
Rossignol, Patrick
Sola, Laura
Usherwood, Tim
Wheeler, David C.
Cho, Yeoungjee
Howell, Martin
Guha, Chandana
Scholes Robertson, Nicole
Widders, Katherine
Matus González, Andrea
Teixeira Pinto, Armando
Viecelli, Andrea K.
Bernier Jean, Amelie
Anumudu, Samaya
Dunn, Louese
Wilkie, Martin
Craig, Jonathan C.
Institución
Resumen
Background: Globally, over 1.2 million people die from chronic kidney disease (CKD) every year. Patients with CKD are up to 10 times more likely to die prematurely than progress to kidney failure requiring kidney replacement therapy. The burden of symptoms and impaired quality of life in CKD may be compounded by comorbidities and treatment side effects. However, patient-important outcomes remain inconsistently and infrequently reported in trials in patients with CKD, which can limit evidence-informed decision-making. The Standardised Outcomes in Nephrology - Chronic Kidney Disease (SONG-CKD) aims to establish a consensus-based core outcome set for trials in patients with CKD not yet requiring kidney replacement therapy to ensure outcomes of relevance to patients, caregivers and health professionals are consistently reported in trials.
Methods: SONG-CKD involves four phases: a systematic review to identify outcomes (domains and measures) that have been reported in randomised controlled trials involving adults with CKD who do not require kidney replacement therapy; stakeholder key informant interviews with health professionals involved in the care of adults with CKD to ascertain their views on establishing core outcomes in CKD; an international two-round online Delphi survey with patients, caregivers, clinicians, researchers, policy makers and industry representatives to obtain consensus on critically important outcome domains; and stakeholder consensus workshops to review and finalise the set of core outcome domains for trials in CKD.
Discussion: Establishing a core outcome set to be reported in trials in patients with CKD will enhance the relevance, transparency and impact of research to improve the lives of people with CKD.
Ítems relacionados
Mostrando ítems relacionados por Título, autor o materia.
-
Dimensional Structure of the Clinical Outcomes in Routine Evaluation - Outcome Measure (CORE-OM) in Mexican University Students
Sosa-Torralba, Janett Esmeralda; Romero-Mendoza, Martha Patricia; Medina-Mora-Icaza, María Elena; Méndez-Ríos, Enrique; Blum-Grynberg, Bertha -
Stakeholders and unintended outcomes in strategic communication
López del Castillo Wilderbeek, Francisco I.