Artículos de revistas
Cardiac remodeling induced by smoking: Concepts, relevance, and potential mechanisms
Inflammation and Allergy - Drug Targets, v. 11, n. 6, p. 442-447, 2012.
Universidade Estadual Paulista (UNESP)
Cardiac or ventricular remodeling is characterized by molecular, cellular, and interstitial alterations that lead to changes in heart size, mass, geometry and function in response to a given insult. Currently, tobacco smoke exposure is recognized as one of these insults. Indeed, tobacco smoke exposure induces the enlargement of the left-sided cardiac chambers, myocardial hypertrophy, and ventricular dysfunction. Potential mechanisms for these alterations include hemodynamic and neurohormonal changes, oxidative stress, inflammation, nitric oxide bioavailability, matrix metalloproteinases and mitogen-activated protein kinase activation. This review will focus on the concepts, relevance, and potential mechanisms of cardiac remodeling induced by tobacco smoke. © 2012 Bentham Science Publishers.
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Minicucci, Marcos Ferreira; Gaiolla, Paula Schmidt Azevedo; Polegato, Bertha Furlan; Paiva, Sergio A.R.; Zornoff, Leonardo Antonio Mamede
β-carotene attenuates the paradoxical effect of tobacco smoke on the mortality of rats after experimental myocardial infarction Paiva, Sergio Alberto Rupp de; Novo, Rosangela; Matsubara, Beatriz Bojikian; Matsubara, Luiz Shiguero; Gaiolla, Paula Schmidt Azevedo; Minicucci, Marcos Ferreira; Campana, Álvaro O.; Zornoff, Leonardo Antonio Mamede
β-carotene attenuates the paradoxical effect of tobacco smoke on the mortality of rats after experimental myocardial infarction Universidade Estadual Paulista (UNESP) (2005-09-01)The objective of this study was to investigate the effects of exposure to tobacco smoke (ETS) in rats that were or were not supplemented with dietary β-carotene (BC), on ventricular remodeling and survival after myocardial ...