Artículos de revistas
An alternative in vitro method for testing the potency of the polyvalent antivenom produced in Costa Rica
Fecha
1988Registro en:
0041-0101
10.1016/0041-0101(88)90010-4
Autor
Gutiérrez, José María
Ávila Agüero, Claudio
Cerdas Fallas, Luis
Rojas Umaña, Ermila
Cerdas Fallas, Luis
Institución
Resumen
The ability of several batches of polyvalent antivenom to neutralize indirect hemolytic activity of Bothrops asper venom was studied using a sensitive plate test. All samples of antivenom tested effectively neutralized this activity. A highly significant correlation was observed between neutralization of indirect hemolysis and neutralization of lethal activity. This simple and sensitive in vitro test could be used to monitor antibody levels in horses immunized to produce polyvalent antivenom.