Artículos de revistas
Uses and misuses of definitions of genetic polymorphism: A perspective from population pharmacogenetics
Fecha
1991Registro en:
1365-2125
10.1111/j.1365-2125.1991.tb03870.x
Autor
Arias, Tomas D.
Jorge, L. F.
Barrantes Mesén, Ramiro
Institución
Resumen
Definitions of genetic polymorphism currently employed
in the pharmacological literature have been incorrectly
used (Kalow, 1984) and uncritically imported from
population genetics [e.g., Weinshilboum (1984), Evans
(1977)], apparently without regard to the problems their
application might present in pharmacogenetics or, more
specifically, in pharmacogenetic studies of populations.