Artículos de revistas
Myocardial Deformation by Speckle Tracking in Severe Dilated Cardiomyopathy
Fecha
2012Registro en:
ARQUIVOS BRASILEIROS DE CARDIOLOGIA, RIO DE JANEIRO, v. 99, n. 3, supl. 1, Part 1-2, pp. 834-841, SEP, 2012
0066-782X
10.1590/S0066-782X2012005000086
Autor
Donadio Abduch, Maria Cristina
Salgo, Ivan
Tsang, Wendy
Campos Vieira, Marcelo Luiz
Cruz, Victoria
Lima, Marta
Tsutsui, Jeane Mike
Mor-Avi, Victor
Lang, Roberto M.
Mathias, Wilson, Jr.
Institución
Resumen
Background: The high and increasing prevalence of Dilated Cardiomyopathy (DCM) represents a serious public health issue. Novel technologies have been used aiming to improve diagnosis and the therapeutic approach. In this context, speckle tracking echocardiography (STE) uses natural myocardial markers to analyze the systolic deformation of the left ventricle (LV). Objective: Measure the longitudinal transmural global strain (GS) of the LV through STE in patients with severe DCM, comparing the results with normal individuals and with echocardiographic parameters established for the analysis of LV systolic function, in order to validate the method in this population. Methods: Seventy-one patients with severe DCM (53 +/- 12 years, 72% men) and 20 controls (30 +/- 8 years, 45% men) were studied. The following variables were studied: LV volumes and ejection fraction calculated by two and three-dimensional echocardiography, Doppler parameters, Tissue Doppler Imaging systolic and diastolic LV velocities and GS obtained by STE. Results: Compared with controls, LV volumes were higher in the DCM group; however, LVEF and peak E-wave velocity were lower in the latter. The myocardial performance index was higher in the patient group. Tissue Doppler myocardial velocities (S', e', a') were significantly lower and E/e' ratio was higher in the DCM group. GS was decreased in the DCM group (-5.5% +/- 2.3%) when compared with controls (-14.0% +/- 1.8%). Conclusion: In this study, GS was significantly lower in patients with severe DCM, bringing new perspectives for therapeutic approaches in this specific population. (Arq Bras Cardiol 2012;99(3):834-842)