Artículos de revistas
Effects of sidestream cigarette smoke exposure on baroreflex components in spontaneously hypertensive rats
Fecha
2010Registro en:
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH, v.20, n.6, p.431-437, 2010
0960-3123
10.1080/09603123.2010.491852
Autor
VALENTI, Vitor E.
ABREU, Luiz Carlos
SALDIVA, Paulo H.
CARVALHO, Tatiana D.
FERREIRA, Celso
Institución
Resumen
We evaluated short-term effects of sidestream cigarette smoke (SSCS) exposure on baroreflex function in spontaneously hypertensive rats (SHR) and Wistar Kyoto (WKY) normotensive rats. Rats were exposed to SSCS during three weeks, 180min, five days per week, in a concentration of carbon monoxide (CO) between 100 and 300ppm. We observed that SSCS exposure increased tachycardic peak and heart rate range while it attenuated bradycardic reflex in WKY. In respect to SHR, SSCS also increased tachycardic peak. Taken together, our data suggests that three weeks of exposure to SSCS affects the sympathetic and parasympathetic component of the baroreflex in normotensive WKY while it tended to affect the sympathetic component in SHR.