Artículos de revistas
Inflammatory epidermolysis bullosa acquisita - Case report
Fecha
2009Registro en:
ANAIS BRASILEIROS DE DERMATOLOGIA, v.84, n.2, p.181-184, 2009
0365-0596
Autor
FERNANDES, Marcelo D`Ambrosio
CHIMINAZZO, Mariana Discacciati
TEBCHERANI, Antonio Jose
AOKI, Valeria
SANCHEZ, Ana Paula Galli
Institución
Resumen
We report a case of an inflammatory variant of epidermolysis bullosa acquisita in a 53-year-old male, with itching blistering eruption on the trunk, armpits and limbs for six months. The skin biopsy specimen showed subepidermal blister with neutrophils. Direct immunofluorescence revealed linear depositions of IgG, IgA, IgM and C3 at the basement membrane; indirect immunofluorescence and salt split skin were negative. Antinuclear antibodies were also negative. Improvement of the blisters followed treatment with systemic corticotherapy and some lesions healed with milia. This is a rare presentation of epidermolysis bullosa acquisita, with inflammatory lesions at first.