Artículos de revistas
New Mixed Li/Mg and Li/Mg/Zn Amides for the Chemoselective Metallation of Arenes and Heteroarenes
Fecha
2009Registro en:
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, n.11, p.1781-1795, 2009
1434-193X
10.1002/ejoc.200801277
Autor
ROHBOGNER, Christoph J.
WUNDERLICH, Stefan H.
CLOSOSKI, Giuliano C.
KNOCHEL, Paul
Institución
Resumen
New mixed Li/Mg and Li/Mg/Zn amides have been synthesized starting from readily prepared secondary amines. They allow a highly chemoselective directed magnesiation or zincation of various polyfunctional aromatics and heteroaromatics. The kinetic basicity, solubility and stability of these new bases have been compared with those of the corresponding 2,2,6,6-tetramethylpiperamide-derived bases. ((c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)