Artículos de revistas
Cytotoxin produced by Escherichia coli isolated from chickens with swollen head syndrome (SHS)
Veterinary Microbiology. Elsevier Science Bv, v. 62, n. 2, n. 111, n. 119, 1998.
This study was conducted to determine the presence of selected virulence factors in Escherichia coil recovered from swollen head syndrome (SHS) in chickens. Thirty-six (72%) of 50 isolates of E. coli from SHS were shown to produce a cytotoxin that was active on Vero and HeLa but not on Y-1 cells. The toxin was called VT2y because the cytotoxic effect on Vero cells was morphologically similar to that produced by E. coli verotoxins (VTs), and this effect was neutralized by antiserum against VT2 but not by antiserum against VT1. Interestingly, DNA probes for VT1 and VT2 failed to hybridize the VT2y-positive isolates with total DNA. Although the role of this toxin in SHS has yet to be demonstrated, the marked edema which characterizes affected chickens is consistent with the action of a toxin such as verotoxin which targets vascular endothelium. (C) 1998 Elsevier Science B.V. All rights reserved.622111119