Artículos de revistas
Elastic liposomes containing benzophenone-3 for sun protection factor enhancement
Registro en:
Pharmaceutical Development And Technology. Informa Healthcare, v. 17, n. 6, n. 661, n. 665, 2012.
1083-7450
WOS:000311897000003
10.3109/10837450.2011.580762
Autor
Severino, P
Moraes, LF
Zanchetta, B
Souto, EB
Santana, MHA
Institución
Resumen
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) This work was focused on the loading of benzophenone-3 in elastic liposomes composed of egg phosphatidylcholine and cholesterol, prepared by the Bangham method. Samples were characterized in terms of particle size, polydispersity index (PI), zeta potential, encapsulation efficiency and in vitro photoprotection properties. The extrusion of liposomes loading benzophenone-3 produced reduced-size (100 nm) elastic liposomes with a PI of 0.2. The active was loaded with a concentration of 20.34% (m/m) revealing changes in the ultraviolet properties after loading. On the basis of these results, it can be anticipated that liposomes are able to improve sun protector factor in vitro compared the free active. 17 6 661 665 Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Rede de Nanocosmeticos Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)