Artículos de revistas
Associated Factors With Survivals In Patients Undergoing Orthotopic Heart Transplant Using Retrograde Blood Microcardioplegia [fatores Associados à Sobrevida Em Pacientes Submetidos A Transplante Cardíaco Utilizando Microcardioplegia Sanguínea Retrógrada]
Registro en:
Brazilian Journal Of Cardiovascular Surgery. , v. 27, n. 3, p. 347 - 354, 2012.
1027638
10.5935/1678-9741.20120061
2-s2.0-84872017557
Autor
Lavagnoli C.F.R.
Severino E.S.B.O.
Vilarinho K.A.S.
Filho L.M.S.
de Oliveira P.P.M.
Petrucci O.
Vieira R.W.
Braile D.M.
Institución
Resumen
Background: Several techniques and cardioplegic solutions have been used for heart preservation during transplant procedures. Unfortunately, there is a lack of ideal method for myocardial preservation in the clinical practice. The use of retrograde cardioplegia provides continuous infusion of cardioplegic solution during the graft implantation. This strategy may provide better initial recovery of the graft. The objective of this study is to describe the experience of a single center where all patients received the same solution for organ preservation and were subjected to continuous retrograde blood microcardioplegia during implantation of the graft and to evaluate factors associated to early and late mortality with this technique. Methods: This is a retrospective, observational and descriptive study of a single center. Results: During the study period were performed 35 heart transplants. Fifteen (42.9%) patients were in cardiogenic shock. The probability of survival was 74.8±7.8%, 60.4±11.3% and 15.1±13.4% at 1 year, 5 years and 10 years of follow-up, respectively. The median survival time was 96.6 months. Conclusion: The use of myocardial protection with retrograde cardioplegic solution may reduce the risks associated morbidity due to cold ischemia time during the heart transplant, and we suggest that this benefit may be even greater in cases of cold ischemia time longer ensuring protection to the myocardium. 27 3 347 354 Carrier, M., Leung, T.K., Solymoss, B.C., Cartier, R., Leclerc, Y., Pelletier, L.C., Clinical trial of retrograde warm blood reperfusion versus standard cold topical irrigation of transplanted hearts (1996) Ann Thorac Surg., 61 (5), pp. 1310-1314 Zeng, Z., Jiang, Z., Wang, C.S., Luo, H., Huang, Y.F., Jin, X.H., Preoperative evaluation improves the outcome in heart transplant recipients with pulmonary hypertension--retrospective analysis of 106 cases (2010) Transplant Proc., 42 (9), pp. 3708-3710 Rossi, D., Pinna, G.D., La Rovere, M.T., Traversi, E., Prognostic significance of tissue-Doppler imaging in chronic heart failure patients on transplant waiting list: A comparative study with right heart catheterization (2011) Eur J Echocardiogr., 12 (2), pp. 112-119 Lichtenstein, S.V., Abel, J.G., Panos, A., Slutsky, A.S., Salerno, T.A., Warm heart surgery: Experience with long cross-clamp times (1991) Ann Thorac Surg., 52 (4), pp. 1009-1013 Juffe Stein, A., New frontiers in myocardial preservation (1995) Rev Esp Cardiol., 48 (SUPPL. 7), pp. 24-28 Wheeldon, D., Sharples, L., Wallwork, J., English, T., Donor heart preservation survey (1992) J Heart Lung Transplant., 11 (5), pp. 986-993 Braile, D., Como eu faço: Cardioplegia sanguínea isotérmica retrógrada de baixo volume (1992) Rev Bras Cir Cardiovasc., 7 (3), pp. 221-229 Bacal, F., Souza Neto, J.D., Fiorelli, A.I., Mejia, J., Marcondes-Braga, F.G., Mangini, S., II Diretriz Brasileira de Transplante Cardíaco (2009) Arq Bras Cardiol., 94 (1 SUPPL. 1), pp. e16-e73 Yacoub, M.P., Mankad, P., Ledingham, S., Donor procurement and surgical techniques for cardiac transplantation (1990) Semin Thorac Cardiovasc Surg., 2 (2), pp. 153-161 Sievers, H.H., Weyand, M., Kraatz, E.G., Bernhard, A., An alternative technique for orthotopic cardiac transplantation, with preservation of the normal anatomy of the right atrium (1991) Thorac Cardiovasc Surg., 39 (2), pp. 70-72 Dreyfus, G., Jebara, V., Mihaileanu, S., Carpentier, A.F., Total orthotopic heart transplantation: An alternative to the standard technique (1991) Ann Thorac Surg., 52 (5), pp. 1181-1184 Aziz, T., Burgess, M., Khafagy, R., Wynn Hann, A., Campbell, C., Rahman, A., Bicaval and standard techniques in orthotopic heart transplantation: Medium-term experience in cardiac performance and survival (1999) J Thorac Cardiovasc Surg., 118 (1), pp. 115-122 Trento, A., Czer, L.S., Blanche, C., Surgical techniques for cardiac transplantation (1996) Semin Thorac Cardiovasc Surg., 8 (2), pp. 126-132 Branco, J.N.R., Teles, C.A., Aguiar, L.F., Vargas, G.F., Hossne Jr., M.A., Andrade, J.C.S., Transplante cardíaco ortotópico: Experiência na Universidade Federal de São Paulo (1998) Rev Bras Cir Cardiovasc., 13 (4), pp. 285-294 Assef, M.A.S., Valbuena, P.F.M.F., Neves Jr., M.T., Correia, E.B., Vasconcelos, M., Manrique, R., Transplante cardíaco no Instituto Dante Pazzanese de Cardiologia: Análise da sobrevida (2001) Rev Bras Cir Cardiovasc., 16 (4), pp. 289-304 Loganathan, S., Radovits, T., Hirschberg, K., Korkmaz, S., Koch, A., Karck, M., Effects of Custodiol-N, a novel organ preservation solution, on ischemia/reperfusion injury (2010) J Thorac Cardiovasc Surg., 139 (4), pp. 1048-1056 Corps, C.L., Attia, M.S., Potts, D., Lodge, J.P., PBSH: A new improved cardiac preservation solution in comparison with three clinically proven solutions (2010) Transplant Proc., 42 (5), pp. 1587-1590 Lee, S., Huang, C.S., Kawamura, T., Shigemura, N., Stolz, D.B., Billiar, T.R., Superior myocardial preservation with HTK solution over Celsior in rat hearts with prolonged cold ischemia (2010) Surgery., 148 (2), pp. 463-473 Wu, K., Türk, T.R., Rauen, U., Su, S., Feldkamp, T., de Groot, H., Prolonged cold storage using a new histidine-tryptophanketoglutarate-based preservation solution in isogeneic cardiac mouse grafts (2011) Eur Heart J., 32 (4), pp. 509-516 Martins, A.S., Silva, M.A., Padovani, C.R., Matsubara, B.B., Braile, D.M., Catâneo, A.J., Myocardial protection by continuous, blood, antegrade-retrograde cardioplegia in rabbits (2007) Acta Cir Bras., 22 (1), pp. 43-46 Carrier, M., Grégoire, J., Khalil, A., Thai, P., Latour, J.G., Pelletier, L.C., Myocardial distribution of retrograde cardioplegic solution assessed by myocardial thallium 201 uptake (1994) J Thorac Cardiovasc Surg, 108 (6), pp. 1115-1118 Ikonomidis, J.S., Yau, T.M., Weisel, R.D., Hayashida, N., Fu, X., Komeda, M., Optimal flow rates for retrograde warm cardioplegia (1994) J Thorac Cardiovasc Surg., 107 (2), pp. 510-519 Fiocchi, R., Vernocchi, A., Mammana, C., Iamele, L., Gamba, A., Continuous retrograde warm blood reperfusion reduces cardiac troponin I release after heart transplantation: A prospective randomized study (2000) Transpl Int., 13 (SUPPL. 1), pp. S240-S244 Suzuki, S., Sasaki, H., Matsuo, T., Tomita, E., Sada, M., Mizuochi, I., Experimental heart transplantation in dogs: Preservation of isolated hearts for 36 hours by retrograde coronary sinus microperfusion (1984) Nippon Geka Gakkai Zasshi., 85 (6), pp. 541-547 Jung, S.H., Kim, J.J., Choo, S.J., Yun, T.J., Chung, C.H., Lee, J.W., Longterm mortality in adult orthotopic heart transplant recipients (2011) J Korean Med Sci., 26 (5), pp. 599-603