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Human hantavirus infections: epidemiology, clinical features, pathogenesis and immunology
(EMH Swiss Medical Publishers, 2014)
In humans, hantaviruses can cause haemorrhagic fever with renal syndrome (HFRS) or hantavirus cardiopulmonary syndrome (HCPS). Currently it is estimated that 150,000 to 200,000 cases of hantavirus disease occur each year, ...
Immunology of Dermatophytosis
(SPRINGER, 2008)
The immune response to infection by dermatophytes ranges from a non-specific host mechanism to a humoral and cell-mediated immune response. The currently accepted view is that a cell-mediated immune response is responsible ...
Immunotherapeutic potential of mollusk hemocyanins in combination with human vaccine adjuvants in murine models of oral cancer
(Hindawi Limited, 2019)
Mollusk hemocyanins have been used for decades in immunological and clinical applications as natural, nontoxic, nonpathogenic, and nonspecific immunostimulants for the treatment of superficial bladder cancer, as ...
New insights to the functional role of the T cell-Antigen Presenting Cell immunological synapse
(Sociedad de Biología de Chile, 2002)
Functional gap junctions accumulate at the immunological synapse and contribute to T cell activation
(2011)
Gap junction (GJ) mediates intercellular communication through linked hemichannels from each of two adjacent cells. Using human and mouse models, we show that connexin 43 (Cx43), the main GJ protein in the immune system, ...
Proteomic identification of heat shock-induced danger signals in a melanoma cell lysate used in dendritic cell-based cancer immunotherapy
(Hindawi Limited, 2018)
Copyright © 2018 Fermín E. González et al. Autologous dendritic cells (DCs) loaded with cancer cell-derived lysates have become a promising tool in cancer immunotherapy. During the last decade, we demonstrated that vaccination ...
Dissociation between plasma and monocyte‐associated cytokines during sepsis
(1991)
We report our investigations of circulating interleukin (IL) 1β, IL 6 and tumor necrosis factor (TNF)‐α, as well as cell‐associated IL 1α, IL 1β and TNF‐α in plasma and monocytes of 21 patients with sepsis syndrome and 6 ...
T lymphocytes activated by persistent viral infection differentially modify the expression of metalloproteinases and their endogenous inhibitors, TIMPs, in human astrocytes: Relevance to HTLV-I-induced neurological disease
(American Association of Immunologists, 2000)
Activation of T lymphocytes by human pathogens is a key step in the development of immune-mediated neurologic diseases. Because of their ability to invade the CNS and their increased secretion of proinflammatory cytokines, ...
Abrogation of prostaglandin E2/EP4 signaling impairs the development of rag1+ lymphoid precursors in the thymus of zebrafish embryos
(American Association of Immunologists, 2007)
PGE2 is involved in a wide variety of physiological and pathological processes; however, deciphering its role in early mammalian development has been difficult due to the maternal contribution of PGE 2. To overcome this ...