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A gathering of neuronal cytoskeletal scientists in South America
(2012)
This essay attempts to capture the spirit of our recent meeting in Chile entitled "Emerging Concepts in Neuronal Cytoskeleton." The purpose of the meeting was to bring together scientists from South American countries with ...
Cellular and molecular mechanisms regulating neuronal growth by brain-derived neurotrophic factor
(Wiley, 2016)
Brain-derived neurotrophic factor (BDNF) and its receptors TrkB and p75 regulate dendritic and axonal growth during development and maintenance of the mature nervous system; however, the cellular and molecular mechanisms ...
Neuronal protein trafficking: Emerging consequences of endoplasmic reticulum dynamics
(2011)
The highly polarized morphology and complex geometry of neurons is determined to a great extent by the structural and functional organization of the secretory pathway. It is intuitive to propose that the spatial arrangement ...
The role of small GTPases in neuronal morphogenesis and polarity
(2012)
The highly dynamic remodeling and cross talk of the microtubule and actin cytoskeleton support neuronal morphogenesis. Small RhoGTPases family members have emerged as crucial regulators of cytoskeletal dynamics. In this ...
Regulation of cytoskeletal dynamics by redox signaling and oxidative stress: implications for neuronal development and trafficking
(Frontiers Media, 2015)
A proper balance between chemical reduction and oxidation (known as redox balance)
is essential for normal cellular physiology. Deregulation in the production of oxidative
species leads to DNA damage, lipid peroxidation ...
The MAP1B case: An old MAP that is new again
(John Wiley, 2014)
The functions of microtubule-associated protein 1B (MAP1B) have historically been linked to the development of the nervous system, based on its very early expression in neurons and glial cells. Moreover, mice in which MAP1B ...
Microtubule configuration and its relationship to sperm morphology in mammalian spermiogenesis
(2008)
The acrosome is a secretory vesicle located in the mammalian sperm head. Its main function is to transport hydrolytic enzymes. These enzymes will dissolve the zona pellucid, assisting the sperm in fertilizing the egg. The ...
Simvastatin disrupts cytoskeleton and decreases cardiac fibroblast adhesion, migration and viability
(Elsevier, 2012)
Statins reduce the isoprenoids farnesyl and geranylgeranyl pyrophosphate, essential intermediates,
which control a diversity of cellular events such as cytoskeleton integrity, adhesion, migration and viability.
Cardiac ...
What Do We Really Know About 5-HT1A Receptor Signaling in Neuronal Cells?
(Frontiers Media, 2016)
Serotonin (5-HT) is a neurotransmitter that plays an important role in neuronal plasticity. Variations in the levels of 5-HT at the synaptic cleft, expression or dysfunction of 5-HT receptors may alter brain development ...