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Intasome architecture and chromatin density modulate retroviral integration into nucleosome
(BioMed Central, 2015)
Background: Retroviral integration depends on the interaction between intasomes, host chromatin and cellular
targeting cofactors as LEDGF/p75 or BET proteins. Previous studies indicated that the retroviral integrase, by ...
Intasome architecture and chromatin density modulate retroviral integration into nucleosome
(BioMed Central Ltd., 2015)
© Benleulmi et al. Background: Retroviral integration depends on the interaction between intasomes, host chromatin and cellular targeting cofactors as LEDGF/p75 or BET proteins. Previous studies indicated that the retroviral ...
Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails
(Biomed Central Ltd., 2017)
Background: Stable insertion of the retroviral DNA genome into host chromatin requires the functional association between the intasome (integrase viral DNA complex) and the nucleosome. The data from the literature suggest ...